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Descriptor English: Diamide
Descriptor Spanish: Diamida
Descriptor diamida
Scope note: Reactivo sulfhidrílico que oxida grupos sulfhidrilo a la forma disulfuro. Es un agente sensibilizador de las radiacines de células anóxicas bacterianas y de mamíferos.
Descriptor Portuguese: Diamida
Descriptor French: Tétraméthyl-diazènedicarboxamide
Entry term(s): Acid Bisdimethylamide, Diazodicarboxylic
Bisdimethylamide, Diazodicarboxylic Acid
Diazodicarboxylic Acid Bis(N,N-dimethyl)amide
Diazodicarboxylic Acid Bisdimethylamide
Dizene Dicarboxylic Acid Bis(N,N-dimethylamide)
Dizenedicarboxylic Acid Bis(N,N-dimethylamide)
Tetramethylazoformamide
Tree number(s): D02.172.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003958
Scope note: A sulfhydryl reagent which oxidizes sulfhydryl groups to the disulfide form. It is a radiation-sensitizing agent of anoxic bacterial and mammalian cells.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Radiation-Sensitizing Agents
Sulfhydryl Reagents
Registry Number: 10465-78-8
CAS Type 1 Name: Diazenedicarboxamide, tetramethyl-
Previous Indexing: Azo Compounds (1966-1976)
Formamides (1966-1976)
Public MeSH Note: 91; was see under AZO COMPOUNDS 1977-90
History Note: 91(77); was see under AZO COMPOUNDS 1977-90
DeCS ID: 3984
Unique ID: D003958
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2000/06/21
Diamide - Preferred
Concept UI M0006203
Scope note A sulfhydryl reagent which oxidizes sulfhydryl groups to the disulfide form. It is a radiation-sensitizing agent of anoxic bacterial and mammalian cells.
Preferred term Diamide
Entry term(s) Acid Bisdimethylamide, Diazodicarboxylic
Bisdimethylamide, Diazodicarboxylic Acid
Diazodicarboxylic Acid Bis(N,N-dimethyl)amide
Diazodicarboxylic Acid Bisdimethylamide
Dizene Dicarboxylic Acid Bis(N,N-dimethylamide)
Dizenedicarboxylic Acid Bis(N,N-dimethylamide)
Tetramethylazoformamide



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