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Descriptor English: Cobra Cardiotoxin Proteins
Descriptor Spanish: Proteínas Cardiotóxicas de Elápidos
Descriptor proteínas cardiotóxicas de cobras
Entry term(s) cardiotoxina de Elapidae
cardiotoxina de Naja
cardiotoxina de cobra
cardiotoxina de elápidos
cardiotoxinas de Naja
cardiotoxinas de cobra
factores líticos directos
proteínas cardiotóxicas de Elapidae
proteínas cardiotóxicas de Naja
Scope note: Polipéptidos básicos de 57 a 62 aminoácidos con cuatro puentes disulfuro y un peso molecular menor de 7.000, que son las proteínas más abundantes del veneno de COBRA. Causan la contracción del músculo esquelético y cardiaco, interfieren en la transmisión neuromuscular y ganglionar, despolarizan las membranas de las células nerviosas, musculares y sanguíneas, causando en consecuencia hemólisis.
Descriptor Portuguese: Proteínas Cardiotóxicas de Elapídeos
Descriptor French: Cardiotoxines de venin de cobra
Entry term(s): Basic Polypeptide, Cardiotoxin-Like
Cardiotoxin I
Cardiotoxin II
Cardiotoxin Like Basic Polypeptide
Cardiotoxin Proteins, Cobra
Cardiotoxin VII 4
Cardiotoxin VII2
Cardiotoxin, Cobra
Cardiotoxin-Like Basic Polypeptide
Cardiotoxins, Elapid
Cobra Cardiotoxin
Cobra Cytotoxin Proteins
Cobra Toxin Gamma
Cobra Venom Cardiotoxin D
Cytotoxin Proteins, Cobra
Cytotoxin-Like Basic Protein (Cobra Venom)
Direct Lytic Factors
Elapid Cardiotoxins
Lytic Factors, Direct
Polypeptide, Cardiotoxin-Like Basic
Toxin Gamma, Cobra
Tree number(s): D12.776.831.222
D20.888.850.325.180
D23.946.833.850.325.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004179
Scope note: Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contraction, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis.
Annotation: /antag permitted but consider also ANTIVENINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Peptides (1966-1977)
Proteins (1966-1977)
Snake Venoms (1975-1977)
Snakes (1966-1974)
Venoms (1966-1974)
Public MeSH Note: 2008; see DIRECT LYTIC FACTORS 1991-2008,` see COBRA VENOMS 1978-1990
History Note: 2008(1978)
DeCS ID: 4239
Unique ID: D004179
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/27
Revision Date: 2017/01/17
Cobra Cardiotoxin Proteins - Preferred
Concept UI M0006549
Scope note Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contraction, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis.
Preferred term Cobra Cardiotoxin Proteins
Entry term(s) Cardiotoxin Proteins, Cobra
Cardiotoxin, Cobra
Cobra Cardiotoxin
Cobra Cytotoxin Proteins
Cytotoxin Proteins, Cobra
Direct Lytic Factors
Lytic Factors, Direct
Cardiotoxin II - Narrower
Concept UI M0006542
Preferred term Cardiotoxin II
Cardiotoxin VII 4 - Narrower
Concept UI M0006543
Preferred term Cardiotoxin VII 4
Cardiotoxin VII2 - Narrower
Concept UI M0006544
Preferred term Cardiotoxin VII2
Cobra Toxin Gamma - Narrower
Concept UI M0006546
Preferred term Cobra Toxin Gamma
Entry term(s) Toxin Gamma, Cobra
Cobra Venom Cardiotoxin D - Narrower
Concept UI M0006547
Preferred term Cobra Venom Cardiotoxin D
Cytotoxin-Like Basic Protein (Cobra Venom) - Narrower
Concept UI M0006548
Preferred term Cytotoxin-Like Basic Protein (Cobra Venom)
Entry term(s) Basic Polypeptide, Cardiotoxin-Like
Cardiotoxin Like Basic Polypeptide
Cardiotoxin-Like Basic Polypeptide
Polypeptide, Cardiotoxin-Like Basic
Cardiotoxin I - Narrower
Concept UI M0006541
Preferred term Cardiotoxin I
Cardiotoxins, Elapid - Broader
Concept UI M0006545
Preferred term Cardiotoxins, Elapid
Entry term(s) Elapid Cardiotoxins



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