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Descriptor English: Three Finger Toxins
Descriptor Spanish: Toxinas de los Tres Dedos
Descriptor toxinas de tres dedos
Entry term(s) 3FTX
NK-3FTX
toxina de tres dedos
tschuditoxina-l
Scope note: Superfamilia de proteínas no enzimáticas presentes en los VENENOS DE ELÁPIDOS. Poseen una estructura terciaria única que se asemeja a una mano con tres dedos y tienen diversas actividades biológicas debido a variaciones secuenciales y estructurales; algunas son alfa-NEUROTOXINAS que se unen a los RECEPTORES NICOTÍNICOS DE ACETILCOLINA.
Descriptor Portuguese: Toxinas Três Dedos
Descriptor French: Toxines à trois doigts
Entry term(s): 3FTXs
Finger Toxin, Three
NK-3FTX
Three Finger Toxin
Three-Finger Toxins
Toxin, Three Finger
Toxins, Three Finger
Toxins, Three-Finger
Tschuditoxin l
Tschuditoxin-l
Tree number(s): D12.776.831.622
D20.888.850.325.600
D23.946.833.850.325.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000087443
Scope note: A super-family of non-enzymatic proteins found in ELAPIDAE VENOMS. They possess a unique tertiary structure resembling a hand with three fingers and have diverse biological activities due to sequence and structural variations; some are ALPHA-NEUROTOXINS that bind NICOTINIC ACETYLCHOLINE RECEPTORS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotoxins
Previous Indexing: Elapid Venoms (1997-2021)
Public MeSH Note: 2022
History Note: 2022
DeCS ID: 59635
Unique ID: D000087443
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/05/10
Three Finger Toxins - Preferred
Concept UI M000737466
Scope note A super-family of non-enzymatic proteins found in ELAPIDAE VENOMS. They possess a unique tertiary structure resembling a hand with three fingers and have diverse biological activities due to sequence and structural variations; some are ALPHA-NEUROTOXINS that bind NICOTINIC ACETYLCHOLINE RECEPTORS.
Preferred term Three Finger Toxins
Entry term(s) 3FTXs
Finger Toxin, Three
Three Finger Toxin
Three-Finger Toxins
Toxin, Three Finger
Toxins, Three Finger
Toxins, Three-Finger
Tschuditoxin-l - Narrower
Concept UI M000738505
Preferred term Tschuditoxin-l
Entry term(s) Tschuditoxin l
NK-3FTX - Narrower
Concept UI M000737467
Scope note Purified toxin from venom of the species NAJA NAJA.
Preferred term NK-3FTX



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