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Descriptor English: Bungarotoxins
Descriptor Spanish: Bungarotoxinas
Descriptor bungarotoxinas
Scope note: Proteínas neurotóxicas del veneno de la krait rayada o de Formosa (Bungarus multicinctus, una serpiente de la familia de los elápidos). La bungarotoxina alfa bloquea los receptores nicotínicos de la acetilcolina y se ha utilizado para aislarlos y estudiarlos; las bungarotoxinas beta y gamma actúan presinápticamente produciendo la liberación y depleción de acetilcolina. Tanto la forma alfa como la beta han sido caracterizadas; la alfa es similar a las neurotoxinas grandes y largas o de tipo II de otros venenos de elápidos.
Descriptor Portuguese: Bungarotoxinas
Descriptor French: Bungarotoxines
Entry term(s): alpha Bungarotoxin
alpha-Bungarotoxin
beta Bungarotoxin
beta-Bungarotoxin
kappa Bungarotoxin
kappa-Bungarotoxin
Tree number(s): D20.888.850.325.139
D23.946.833.850.325.139
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002038
Scope note: Neurotoxic proteins from the venom of the banded or Formosan krait (Bungarus multicinctus, an elapid snake). alpha-Bungarotoxin blocks nicotinic acetylcholine receptors and has been used to isolate and study them; beta- and gamma-bungarotoxins act presynaptically causing acetylcholine release and depletion. Both alpha and beta forms have been characterized, the alpha being similar to the large, long or Type II neurotoxins from other elapid venoms.
Annotation: from the krait, a snake; /antag permitted but consider also ANTIVENINS; alpha-bungarotoxin & beta-bungarotoxin go here
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 74
History Note: 74(73)
DeCS ID: 2070
Unique ID: D002038
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Bungarotoxins - Preferred
Concept UI M0003031
Scope note Neurotoxic proteins from the venom of the banded or Formosan krait (Bungarus multicinctus, an elapid snake). alpha-Bungarotoxin blocks nicotinic acetylcholine receptors and has been used to isolate and study them; beta- and gamma-bungarotoxins act presynaptically causing acetylcholine release and depletion. Both alpha and beta forms have been characterized, the alpha being similar to the large, long or Type II neurotoxins from other elapid venoms.
Preferred term Bungarotoxins
beta-Bungarotoxin - Narrower
Concept UI M0003030
Preferred term beta-Bungarotoxin
Entry term(s) beta Bungarotoxin
kappa-Bungarotoxin - Narrower
Concept UI M0003032
Preferred term kappa-Bungarotoxin
Entry term(s) kappa Bungarotoxin
alpha-Bungarotoxin - Narrower
Concept UI M0003029
Preferred term alpha-Bungarotoxin
Entry term(s) alpha Bungarotoxin



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