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Descriptor English: GTP-Binding Protein alpha Subunit, Gi2
Descriptor Spanish: Subunidad alfa de la Proteína de Unión al GTP Gi2
Descriptor subunidad alfa de la proteína de unión al GTP Gi2
Entry term(s) subunidad alfa de la proteína de unión a GTP Gi2
Scope note: Subunidad alfa de la proteína de unión al GTP sensible a la TOXINA DE PERTUSSIS. Se acopla a diversos RECEPTORES DE LA SUPERFICIE CELULAR, y ha sido implicada en la producción de INTERLEUCINA-12 y puede desempeñar una función en las ENFERMEDADES INTESTINALES INFLAMATORIAS.
Descriptor Portuguese: Subunidade alfa Gi2 de Proteína de Ligação ao GTP
Descriptor French: Sous-unité alpha Gi2 des protéines G
Entry term(s): G Protein Subunit alpha I2
GTP Binding Protein alpha Subunit, Gi2
Galpha(i2) Protein
Galphai2 Protein
Gi2 alpha Protein
Gi2-alpha Protein
Tree number(s): D08.811.277.040.330.300.200.100.200.500
D12.776.157.325.332.100.200.500
D12.776.476.338.200.100.200.500
D12.776.543.325.100.200.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051960
Scope note: A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SURFACE RECEPTORS, has been implicated in INTERLEUKIN-12 production, and may play a role in INFLAMMATORY BOWEL DISEASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.5.1
Public MeSH Note: 2006; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2 was indexed under PROTO-ONCOGENE PROTEINS 1995-2005, & under GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO 2000-2005, & under GTP-BINDING PROTEINS 1994-1999, & under ONCOGENE PROTEINS 1993-1994
History Note: 2006(1993)
DeCS ID: 50578
Unique ID: D051960
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/06/30
GTP-Binding Protein alpha Subunit, Gi2 - Preferred
Concept UI M0212481
Scope note A PERTUSSIS TOXIN-sensitive GTP-binding protein alpha subunit. It couples with a variety of CELL SURFACE RECEPTORS, has been implicated in INTERLEUKIN-12 production, and may play a role in INFLAMMATORY BOWEL DISEASES.
Preferred term GTP-Binding Protein alpha Subunit, Gi2
Entry term(s) G Protein Subunit alpha I2
GTP Binding Protein alpha Subunit, Gi2
Galpha(i2) Protein
Galphai2 Protein
Gi2 alpha Protein
Gi2-alpha Protein



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