DeCS

Descriptor English:

Heterotrimeric GTP-Binding Proteins

Descriptor Spanish:

Proteínas de Unión al GTP Heterotriméricas

Spanish from Spain

Descriptor	proteínas de unión al GTP heterotriméricas
Entry term(s)	proteína G heterotrimérica proteína de unión a GTP heterotrimérica proteína de unión al GTP heterotrimérica proteína heterotrimérica de unión a GTP proteína heterotrimérica de unión al GTP proteínas G heterotriméricas proteínas de unión a GTP heterotriméricas proteínas heterotriméricas G proteínas heterotriméricas de unión a GTP proteínas heterotriméricas de unión al GTP
Scope note:	PROTEÍNAS DE UNIÓN AL GTP que contienen tres subunidades que no son idénticas. Se asocian a miembros de la superfamilia de siete dominios transmembranosos de RECEPTORES ACOPLADOS A PROTEÍNAS G. Al activarse las SUBUNIDADES ALFA DE LAS PROTEÍNAS DE UNIÓN AL GTP el complejo se disocia dando lugar a un dímero de una SUBUNIDAD BETA DE LAS PROTEÍNAS DE UNIÓN AL GTP unido a una SUBUNIDAD GAMMA DE LAS PROTEÍNAS DE UNIÓN AL GTP.

Descriptor Portuguese:

Proteínas Heterotriméricas de Ligação ao GTP

Descriptor French:

Protéines G hétérotrimériques

Entry term(s):

G Protein, Heterotrimeric
G-Proteins, Heterotrimeric
GTP-Binding Proteins, Heterotrimeric
Heterotrimeric G Protein
Heterotrimeric G Proteins
Heterotrimeric G-Protein
Heterotrimeric G-Proteins
Heterotrimeric GTP Binding Proteins
Heterotrimeric GTP-Binding Protein
Protein, Heterotrimeric G

Tree number(s):

D08.811.277.040.330.300.200
D12.776.157.325.332
D12.776.476.338.200
D12.776.543.325

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D020962

Scope note:

GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.

Annotation:

general or unspecified; prefer specifics

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Registry Number:

EC 3.6.5.1

Previous Indexing:

Adenylate Cyclase (1968-1984)
Carrier Proteins (1966-1984)
GTP-Binding Proteins (1985-1999)
Guanine Nucleotides (1966-1984)
Guanosine Triphosphate (1972-1984)
Receptors, Cell Surface (1973-1984)

Concept UI	M0328203
Scope note	GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
Preferred term	Heterotrimeric GTP-Binding Proteins
Entry term(s)	G Protein, Heterotrimeric G-Proteins, Heterotrimeric GTP-Binding Proteins, Heterotrimeric Heterotrimeric G Protein Heterotrimeric G Proteins Heterotrimeric G-Protein Heterotrimeric G-Proteins Heterotrimeric GTP Binding Proteins Heterotrimeric GTP-Binding Protein Protein, Heterotrimeric G

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