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Descriptor English: Ethambutol
Descriptor Spanish: Etambutol
Descriptor etambutol
Scope note: Agente antituberculoso que inhibe la transferencia de ácidos micólicos a la pared celular del bacilo de la tuberculosis. También puede inhibir la síntesis de la espermidina en las micobacterias. Generalmente su acción es bactericida y el ffármaco puede atravesar las membranas de las células humanas para ejercer su efecto letal. (Smith and Reynard, Textbook of Pharmacology, 1992, p863).
Descriptor Portuguese: Etambutol
Descriptor French: Éthambutol
Entry term(s): Dexambutol
EMB Fatol
EMB Hefa
EMB-Fatol
EMB-Hefa
Etambutol Llorente
Ethambutol Hydrochloride
Etibi
Hydrochloride, Ethambutol
Llorente, Etambutol
Miambutol
Myambutol
Tree number(s): D02.092.782.258.368.265
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004977
Scope note: An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antitubercular Agents
Registry Number: 8G167061QZ
CAS Type 1 Name: 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, (S-(R*,R*))-
Public MeSH Note: 68
History Note: 68(63)
DeCS ID: 5069
Unique ID: D004977
NLM Classification: QV 268
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Ethambutol - Preferred
Concept UI M0007814
Scope note An antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. (From Smith and Reynard, Textbook of Pharmacology, 1992, p863)
Preferred term Ethambutol
Dexambutol - Narrower
Concept UI M0477800
Preferred term Dexambutol
Etibi - Narrower
Concept UI M0477798
Preferred term Etibi
Entry term(s) EMB Fatol
EMB-Fatol
Etambutol Llorente - Narrower
Concept UI M0477801
Preferred term Etambutol Llorente
Entry term(s) Llorente, Etambutol
Ethambutol Hydrochloride - Narrower
Concept UI M0007816
Preferred term Ethambutol Hydrochloride
Entry term(s) Hydrochloride, Ethambutol
Myambutol - Narrower
Concept UI M0007815
Preferred term Myambutol
Entry term(s) Miambutol
EMB-Hefa - Narrower
Concept UI M0477799
Preferred term EMB-Hefa
Entry term(s) EMB Hefa



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