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Descriptor English: Methapyrilene
Descriptor Spanish: Metapirileno
Descriptor metapirileno
Entry term(s) tenilpiramina
Scope note: Antagonista de los receptores H1 de la tihistamina con acción sedante, utilizado como hipnótico y en alergias.
Descriptor Portuguese: Metapirileno
Descriptor French: Méthapyrilène
Entry term(s): Lullamin
N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine
Restryl
Tenalin
Thenylpyramine
Thionylan
Tree number(s): D02.092.782.258.368.500
D03.383.725.050.440
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008701
Scope note: Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Histamine H1 Antagonists
Hypnotics and Sedatives
Anti-Allergic Agents
Registry Number: A01LX40298
CAS Type 1 Name: 1,2-Ethanediamine, N,N-dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-
Public MeSH Note: 91; was see under AMINOPYRIDINES 1979-90; was see under PYRIDINES 1975-78; was see under ANTIHISTAMINICS 1963-74
Online Note: use HISTAMINE H1 RECEPTOR BLOCKADERS to search METHAPYRILENE 1966-74
History Note: 91(75); was see under AMINOPYRIDINES 1979-90; was see under PYRIDINES 1975-78; was see under ANTIHISTAMINICS 1963-74
DeCS ID: 8876
Unique ID: D008701
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/12/08
Revision Date: 2016/05/31
Methapyrilene - Preferred
Concept UI M0013559
Scope note Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.
Preferred term Methapyrilene
Entry term(s) N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine
Thenylpyramine
Tenalin - Narrower
Concept UI M0351270
Preferred term Tenalin
Lullamin - Narrower
Concept UI M0351272
Preferred term Lullamin
Restryl - Narrower
Concept UI M0351271
Preferred term Restryl
Thionylan - Narrower
Concept UI M0351269
Preferred term Thionylan



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