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Descriptor English: Phosphoribosylaminoimidazolecarboxamide Formyltransferase
Descriptor Spanish: Fosforribosilaminoimidazolcarboxamida-Formiltransferasa
Descriptor fosforribosilaminoimidazolcarboxamida formiltransferasa
Scope note: Enzima que cataliza la conversión del aminoimidazol-4-carboxamida ribonucleótido a 5-formil-aminoimidazol-4-carboxamida ribonucleótido en la vía de la síntesis de novo de las purinas. Requiera el cofactor N(10)-FORMILTETRAHIDROFOLATO como donante de formilo.
Descriptor Portuguese: Fosforribosilaminoimidazolcarboxamida Formiltransferase
Descriptor French: Phosphoribosylaminoimidazolecarboxamide formyltransferase
Entry term(s): AICAR Formyltransferase
AICAR Transformylase
AICARTFase
Aminoimidazolecarboxamide Ribonucleotide Transformylase
Formyltransferase, AICAR
Formyltransferase, Phosphoribosylaminoimidazolecarboxamide
Ribonucleotide Transformylase, Aminoimidazolecarboxamide
Transformylase, AICAR
Transformylase, Aminoimidazolecarboxamide Ribonucleotide
Tree number(s): D08.811.913.555.400.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051027
Scope note: An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.2.3
CAS Type 1 Name: 5-amino-4-imidazolecarboxamide ribotide transformylase
Public MeSH Note: 2006; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE was indexed under HYDROXYMETHYL AND FORMYL TRANSFERASES 1998-2005, ACYLTRANSFERASES 1980-1997, FORMIC ACIDS 1974-1980, AMINOIMIDAZOLE CARBOXAMIDE 1979-1980, IMIDAZOLES 1974-1979, PENTOSEPHOSPHATES 1974-1979, TRANSFERASES 1974-1979
History Note: 2006(1980); use FORMIC ACIDS 1974-1980, AMINOIMIDAZOLE CARBOXAMIDE 1979-1980, IMIDAZOLES 1974-1979, PENTOSEPHOSPHATES 1974-1979, TRANSFERASES 1974-1979
DeCS ID: 50698
Unique ID: D051027
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2009/07/15
Phosphoribosylaminoimidazolecarboxamide Formyltransferase - Preferred
Concept UI M0078323
Scope note An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
Preferred term Phosphoribosylaminoimidazolecarboxamide Formyltransferase
Entry term(s) AICAR Formyltransferase
AICAR Transformylase
AICARTFase
Aminoimidazolecarboxamide Ribonucleotide Transformylase
Formyltransferase, AICAR
Formyltransferase, Phosphoribosylaminoimidazolecarboxamide
Ribonucleotide Transformylase, Aminoimidazolecarboxamide
Transformylase, AICAR
Transformylase, Aminoimidazolecarboxamide Ribonucleotide



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