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Descriptor English: Glycine Hydroxymethyltransferase
Descriptor Spanish: Glicina Hidroximetiltransferasa
Descriptor glicina hidroximetiltransferasa
Entry term(s) serina aldolasa
serina hidroximetilasa
serina hidroximetiltransferasa
serina transhidroximetilasa
treonina aldolasa
Scope note: Enzima que contiene fosfato de piridoxal y cataliza la reacción de la glicina y 5,10-metileno-tetrahidrofolato para formar serina. También cataliza la reacción de la glicina con acetaldehído para formar L-treonina. EC 2.1.2.1.
Descriptor Portuguese: Glicina Hidroximetiltransferase
Descriptor French: Glycine hydroxymethyltransferase
Entry term(s): Aldolase, Allothreonine
Aldolase, Serine
Aldolase, Threonine
Allothreonine Aldolase
Hydroxymethylase, Serine
Hydroxymethyltransferase, Glycine
Hydroxymethyltransferase, Serine
Serine Aldolase
Serine Hydroxymethylase
Serine Hydroxymethyltransferase
Serine Transhydroxymethylase
Threonine Aldolase
Transhydroxymethylase, Serine
Tree number(s): D08.811.913.555.400.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012696
Scope note: A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.2.1
CAS Type 1 Name: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Previous Indexing: Serine (1973-1974)
Tetrahydrofolates (1973-1974)
Transferases (1973-1974)
Public MeSH Note: 98; see SERINE HYDROXYMETHYLTRANSFERASE 1991-97, see TRANSFERASES 1975-90
History Note: 98(75)
DeCS ID: 13076
Unique ID: D012696
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09
Glycine Hydroxymethyltransferase - Preferred
Concept UI M0019677
Scope note A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.
Preferred term Glycine Hydroxymethyltransferase
Entry term(s) Aldolase, Allothreonine
Aldolase, Serine
Aldolase, Threonine
Allothreonine Aldolase
Hydroxymethylase, Serine
Hydroxymethyltransferase, Glycine
Hydroxymethyltransferase, Serine
Serine Aldolase
Serine Hydroxymethylase
Serine Hydroxymethyltransferase
Serine Transhydroxymethylase
Threonine Aldolase
Transhydroxymethylase, Serine



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