| Descriptor English: | Phosphoribosylglycinamide Formyltransferase | ||||
| Descriptor Spanish: |
Fosforribosilglicinamida-Formiltransferasa
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| Descriptor Portuguese: | Fosforribosilglicinamido Formiltransferase | ||||
| Descriptor French: | Phosphoribosylglycinamide formyltransferase | ||||
| Entry term(s): |
2 Amino N Ribosylacetamide 5' Phosphate Transformylase 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase 5' Phosphoribosylglycinamide Transformylase 5'-Phosphate Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphoribosylglycinamide Transformylase Formyltransferase, GAR Formyltransferase, Phosphoribosylglycinamide GAR Formyltransferase GAR Transformylase GARTFase Glycinamide Ribonucleotide Transformylase Glycinamideribotide Transformylase Ribonucleotide Transformylase, Glycinamide Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase, 5'-Phosphoribosylglycinamide Transformylase, GAR Transformylase, Glycinamide Ribonucleotide Transformylase, Glycinamideribotide |
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| Tree number(s): |
D08.811.913.555.400.750 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051026 | ||||
| Scope note: | An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.1.2.2 | ||||
| Public MeSH Note: | 2006; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE was indexed under HYDROXYMETHYL AND FORMYL TRANSFERASES 1998-2005, ACYLTRANSFERASES 1979-1997, GLYCINE 1974-1980, FORMIC ACIDS 1974-1982, GLYCINE 1980-1982, PENTOSEPHOSPHATES 1974-1975, RIBOSEMONOPHOSPHATES 1975-1980, & under TRANSFERASES 1974-1978 |
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| History Note: | 2006(1980); use ACYLTRANSFERASES 1979, GLYCINE 1974-1979, FORMIC ACIDS 1974-1979, PENTOSEPHOSPHATES 1974-1975, RIBOSEMONOPHOSPHATES 1975-1979, & TRANSFERASES 1974-1978 |
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| DeCS ID: | 50699 | ||||
| Unique ID: | D051026 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 | ||||
| Revision Date: | 2013/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Phosphoribosylglycinamide Formyltransferase
- Preferred
| Concept UI |
M0078358 |
| Scope note | An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway. |
| Preferred term | Phosphoribosylglycinamide Formyltransferase |
| Entry term(s) |
2 Amino N Ribosylacetamide 5' Phosphate Transformylase 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase 5' Phosphoribosylglycinamide Transformylase 5'-Phosphate Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphoribosylglycinamide Transformylase Formyltransferase, GAR Formyltransferase, Phosphoribosylglycinamide GAR Formyltransferase GAR Transformylase GARTFase Glycinamide Ribonucleotide Transformylase Glycinamideribotide Transformylase Ribonucleotide Transformylase, Glycinamide Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase, 5'-Phosphoribosylglycinamide Transformylase, GAR Transformylase, Glycinamide Ribonucleotide Transformylase, Glycinamideribotide |
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