| Descriptor English: | Cyclin-Dependent Kinase 6 | ||||||
| Descriptor Spanish: |
Quinasa 6 Dependiente de la Ciclina
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| Descriptor Portuguese: | Quinase 6 Dependente de Ciclina | ||||||
| Descriptor French: | Kinase-6 cycline-dépendante | ||||||
| Entry term(s): |
CDK6 Protein Cdk6 Protein Kinase Cell Division Protein Kinase 6 Cyclin Dependent Kinase 6 PLSTIRE Protein Protein Kinase, Cdk6 |
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| Tree number(s): |
D08.811.913.696.620.682.700.646.500.937 D12.776.167.200.515 D12.776.476.563.646.500.937 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051361 | ||||||
| Scope note: | Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during G1 PHASE of the CELL CYCLE. It helps regulate the transition to S PHASE and its kinase activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P18. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.22 | ||||||
| Public MeSH Note: | 2006; CYCLIN-DEPENDENT KINASE 6 was indexed under CYCLIN-DEPENDENT KINASES 2003-2005, & under PROTEIN-SERINE-THREONINE KINASES 1995-2002, & under PROTEIN KINASES 1994 |
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| History Note: | 2006(1994) |
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| DeCS ID: | 50716 | ||||||
| Unique ID: | D051361 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Cyclin-Dependent Kinase 6
- Preferred
| Concept UI |
M0228003 |
| Scope note | Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during G1 PHASE of the CELL CYCLE. It helps regulate the transition to S PHASE and its kinase activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P18. |
| Preferred term | Cyclin-Dependent Kinase 6 |
| Entry term(s) |
CDK6 Protein Cdk6 Protein Kinase Cell Division Protein Kinase 6 Cyclin Dependent Kinase 6 PLSTIRE Protein Protein Kinase, Cdk6 |
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