| Descriptor English: | Cyclin-Dependent Kinase 4 | ||||||
| Descriptor Spanish: |
Quinasa 4 Dependiente de la Ciclina
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| Descriptor Portuguese: | Quinase 4 Dependente de Ciclina | ||||||
| Descriptor French: | Kinase-4 cycline-dépendante | ||||||
| Entry term(s): |
Cdk4 Cyclin Dependent Kinase Cdk4 Cyclin-Dependent Kinase Cdk4 Protein Cdk4 Protein Kinase Cell Division Protein Kinase 4 Cyclin D Dependent Kinase CDK4 Cyclin D-Dependent Kinase CDK4 Cyclin Dependent Kinase 4 Cyclin-Dependent Kinase, Cdk4 PSK J3 Kinase PSK-J3 Kinase Protein Kinase, Cdk4 p34PSK J3 Kinase p34PSK-J3 Kinase |
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| Tree number(s): |
D08.811.913.696.620.682.700.646.500.875 D12.776.167.200.451 D12.776.476.563.646.500.875 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D051358 | ||||||
| Scope note: | Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.22 | ||||||
| Public MeSH Note: | 2006; CYCLIN-DEPENDENT KINASE 4 was indexed under CYCLIN-DEPENDENT KINASES & PROTO-ONCOGENE PROTEINS 2005, CELL CYCLE PROTEINS 1992-2004, PROTEIN SERINE THREONINE KINASES 1995, & under PROTEIN KINASES 1992-1994 |
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| History Note: | 2006(1992) |
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| DeCS ID: | 50715 | ||||||
| Unique ID: | D051358 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2015/11/23 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Cyclin-Dependent Kinase 4
- Preferred
| Concept UI |
M0208277 |
| Scope note | Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16. |
| Preferred term | Cyclin-Dependent Kinase 4 |
| Entry term(s) |
Cdk4 Cyclin Dependent Kinase Cdk4 Cyclin-Dependent Kinase Cdk4 Protein Cdk4 Protein Kinase Cell Division Protein Kinase 4 Cyclin D Dependent Kinase CDK4 Cyclin D-Dependent Kinase CDK4 Cyclin Dependent Kinase 4 Cyclin-Dependent Kinase, Cdk4 PSK J3 Kinase PSK-J3 Kinase Protein Kinase, Cdk4 p34PSK J3 Kinase p34PSK-J3 Kinase |
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