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Descriptor English: STAT2 Transcription Factor
Descriptor Spanish: Factor de Transcripción STAT2
Descriptor factor de transcripción STAT2
Scope note: Transductor de señales y activador de la transcripción que media en las respuestas celulares a los INTERFERONES DE TIPO I. La proteína Stat2 se asocia constitutivamente con el FACTOR 9 REGULADOR DEL INTERFERÓN. Después de la FOSFORILACIÓN, Stat2 forma el COMPLEJO FACTOR 3 DE GENES ESTIMULADOS POR EL INTERFERÓN para regular la expresión de los GENES diana.
Descriptor Portuguese: Fator de Transcrição STAT2
Descriptor French: Facteur de transcription STAT-2
Entry term(s): Factor STAT2, Transcription
STAT2 Protein
Signal Transducer and Activator of Transcription 2
Transcription Factor STAT2
Transcription Factor, STAT2
Tree number(s): D12.644.360.024.303.500.750
D12.644.360.024.342.200
D12.776.157.057.061.500.750
D12.776.157.057.186.200
D12.776.260.513.249.750
D12.776.476.024.386.500.750
D12.776.476.024.430.200
D12.776.930.354.249.750
D12.776.930.840.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050795
Scope note: A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; STAT2 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1995-2005
History Note: 2006(1995)
DeCS ID: 50772
Unique ID: D050795
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18
STAT2 Transcription Factor - Preferred
Concept UI M0244035
Scope note A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.
Preferred term STAT2 Transcription Factor
Entry term(s) Factor STAT2, Transcription
STAT2 Protein
Signal Transducer and Activator of Transcription 2
Transcription Factor STAT2
Transcription Factor, STAT2



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