| Descriptor English: | STAT3 Transcription Factor | ||||
| Descriptor Spanish: |
Factor de Transcripción STAT3
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| Descriptor Portuguese: | Fator de Transcrição STAT3 | ||||
| Descriptor French: | Facteur de transcription STAT-3 | ||||
| Entry term(s): |
APRF Transcription Factor Acute Phase Response Factor Acute-Phase Response Factor IL6 Response Factor IL6-Response Factor LIF Response Factor LIF-Response Factor Response Factor, Acute-Phase STAT3 Protein STAT3a Transcription Factor STAT3b Transcription Factor Signal Transducer and Activator of Transcription 3 Stat3alpha Transcription Factor Stat3beta Transcription Factor Transcription Factor, APRF Transcription Factor, STAT3 Transcription Factor, STAT3a Transcription Factor, STAT3b Transcription Factor, Stat3alpha Transcription Factor, Stat3beta |
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| Tree number(s): |
D12.644.360.024.342.300 D12.776.157.057.186.300 D12.776.476.024.430.300 D12.776.930.840.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050796 | ||||
| Scope note: | A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2006; STAT3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSACTIVATORS 1994-2005 |
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| History Note: | 2006 |
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| Related: |
src Homology Domains
MeSH | ||||
| DeCS ID: | 50796 | ||||
| Unique ID: | D050796 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 | ||||
| Revision Date: | 2016/02/18 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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STAT3 Transcription Factor
- Preferred
STAT3b Transcription Factor
- Narrower
STAT3a Transcription Factor
- Narrower
| Concept UI |
M0229085 |
| Scope note | A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130. |
| Preferred term | STAT3 Transcription Factor |
| Entry term(s) |
APRF Transcription Factor Acute Phase Response Factor Acute-Phase Response Factor IL6 Response Factor IL6-Response Factor LIF Response Factor LIF-Response Factor Response Factor, Acute-Phase STAT3 Protein Signal Transducer and Activator of Transcription 3 Transcription Factor, APRF Transcription Factor, STAT3 |
| Concept UI |
M0229081 |
| Preferred term | STAT3b Transcription Factor |
| Entry term(s) |
Stat3beta Transcription Factor Transcription Factor, STAT3b Transcription Factor, Stat3beta |
| Concept UI |
M0229080 |
| Preferred term | STAT3a Transcription Factor |
| Entry term(s) |
Stat3alpha Transcription Factor Transcription Factor, STAT3a Transcription Factor, Stat3alpha |
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