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Descriptor English: Smad7 Protein
Descriptor Spanish: Proteína smad7
Descriptor proteína smad7
Scope note: Proteína smad inhibidora que se asocia a los RECEPTORES DEL FACTOR DEL CRECIMIENTO TRANSFORMADOR BETA y a los RECEPTORES DE PROTEÍNAS MORFOGENÉTICAS ÓSEAS. Regula negativamente las VÍAS DE TRANSDUCCIÓN DE SEÑALES al inhibir la FOSFORILACIÓN de las PROTEÍNAS SMAD REGULADAS POR RECEPTORES.
Descriptor Portuguese: Proteína Smad7
Descriptor French: Protéine Smad7
Entry term(s): Madh7 Protein
Tree number(s): D12.644.360.024.334.200.700
D12.776.157.057.170.249.700
D12.776.476.024.428.249.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051906
Scope note: An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE MORPHOGENETIC PROTEIN RECEPTORS. It negatively regulates SIGNAL TRANSDUCTION PATHWAYS by inhibiting PHOSPHORYLATION of RECEPTOR-REGULATED SMAD PROTEINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; SMAD7 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1997-2005
History Note: 2006(1997)
DeCS ID: 50787
Unique ID: D051906
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18
Smad7 Protein - Preferred
Concept UI M0280200
Scope note An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE MORPHOGENETIC PROTEIN RECEPTORS. It negatively regulates SIGNAL TRANSDUCTION PATHWAYS by inhibiting PHOSPHORYLATION of RECEPTOR-REGULATED SMAD PROTEINS.
Preferred term Smad7 Protein
Entry term(s) Madh7 Protein



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