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Descriptor English: Smad Proteins
Descriptor Spanish: Proteínas Smad
Descriptor proteínas smad
Scope note: Familia de proteínas implicadas en la translocación de señales desde los RECEPTORES TGF-BETA, RECEPTORES DE LAS PROTEÍNAS MORFOGENÉTICAS ÓSEAS y otros receptores de superficie al NÚCLEO CELULAR. Originalmente fueron identificadas como una clase de proteínas relacionadas con la proteína mothers against decapentaplegic, Drosophila y proteínas sma de CAENORHABDITIS ELEGANS.
Descriptor Portuguese: Proteínas Smad
Descriptor French: Protéines Smad
Entry term(s): Mothers Against Decapentaplegic Homolog
Sma- and Mad-Related Proteins
Tree number(s): D12.644.360.024.334
D12.776.157.057.170
D12.776.260.713
D12.776.476.024.428
D12.776.930.806
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051785
Scope note: A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.
Annotation: general; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; SMAD PROTEINS was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1996-2005
History Note: 2006(1996)
DeCS ID: 50784
Unique ID: D051785
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18
Smad Proteins - Preferred
Concept UI M0418709
Scope note A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.
Preferred term Smad Proteins
Entry term(s) Mothers Against Decapentaplegic Homolog
Sma- and Mad-Related Proteins



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