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Descriptor English: Synaptotagmin I
Descriptor Spanish: Sinaptotagmina I
Descriptor sinaptotagmina I
Scope note: Proteína de transporte vesicular expresada predominantemente en las NEURONAS. La sinaptotagmina ayuda a regular la EXOCITOSIS de las VESÍCULAS SINÁPTICAS y parece servir como sensor de calcio para desencadenar la liberación de NEUROTRANSMISORES. Actúa también como receptor de la célula nerviosa de ciertas TOXINAS BOTULÍNICAS.
Descriptor Portuguese: Sinaptotagmina I
Descriptor French: Synaptotagmine I
Entry term(s): Synaptic Vesicle Protein p65
Synaptotagmin 1
p65 Protein (Synaptotagmin I)
Tree number(s): D12.776.157.125.825.249
D12.776.543.990.850.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050863
Scope note: A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; SYNAPTOTAGMIN I was indexed under CALCIUM-BINDING PROTEINS, MEMRANE GLYCOPROTEINS, & NERVE TISSUE PROTEINS 1991-2005
History Note: 2006(1991)
DeCS ID: 50841
Unique ID: D050863
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2010/06/25
Synaptotagmin I - Preferred
Concept UI M0183221
Scope note A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Preferred term Synaptotagmin I
Entry term(s) Synaptic Vesicle Protein p65
Synaptotagmin 1
p65 Protein (Synaptotagmin I)



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