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Descriptor English: Synaptotagmin II
Descriptor Spanish: Sinaptotagmina II
Descriptor sinaptotagmina II
Scope note: Proteína de transporte vesicular caracterizada originalmente como una proteína de unión al inositol polifosfato. La sinaptotagmina ayuda a regular la EXOCITOSIS de las VESÍCULAS SINÁPTICAS y parece servir como sensor de calcio para desencadenar la liberación de NEUROTRANSMISORES. Actúa también como receptor de la célula nerviosa de ciertas TOXINAS BOTULÍNICAS.
Descriptor Portuguese: Sinaptotagmina II
Descriptor French: Synaptotagmine II
Entry term(s): Synaptotagmin 2
Tree number(s): D12.776.157.125.825.500
D12.776.543.990.850.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050861
Scope note: A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; SYNAPTOTAGMIN II was indexed under NERVE TISSUE PROTEINS 1991-2005
History Note: 2006(1991)
DeCS ID: 50842
Unique ID: D050861
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Synaptotagmin II - Preferred
Concept UI M0190840
Scope note A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Preferred term Synaptotagmin II
Entry term(s) Synaptotagmin 2



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