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Descriptor English: Transcription Factor Brn-3C
Descriptor Spanish: Factor de Transcripción Brn-3C
Descriptor factor de transcripción Brn-3C
Entry term(s) factor de transcripción Pou4f3
Scope note: Factor de dominio POU que activa la TRANSCRIPCIÓN de GENES en las neuronas que codifican PROTEÍNAS NEUROFILAMENTOSAS, alfa-internexina y PROTEÍNA 25 ASOCIADA A SINAPTOSOMAS. Las mutaciones en el gen Brn-3c se han relacionado con la SORDERA.
Descriptor Portuguese: Fator de Transcrição Brn-3C
Descriptor French: Facteur de transcription Brn-3C
Entry term(s): Brn 3c Transcription Factor
Brn-3C, Transcription Factor
Brn-3c Transcription Factor
POU Domain, Class 4, Transcription Factor 3
Pou4f3 Transcription Factor
Transcription Factor Brn 3C
Transcription Factor, Brn-3c
Transcription Factor, Pou4f3
Tree number(s): D12.776.260.655.625.500
D12.776.930.710.625.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050821
Scope note: A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha internexin, and SYNAPTOSOMAL-ASSOCIATED PROTEIN 25. Mutations in the Brn-3c gene have been associated with DEAFNESS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; TRANSCRIPTION FACTOR BRN-3C was indexed under TRANSCRIPTION FACTORS & DNA-BINDING PROTEINS 1992-2005
History Note: 2006
DeCS ID: 51043
Unique ID: D050821
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/06/29
Transcription Factor Brn-3C - Preferred
Concept UI M0208058
Scope note A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha internexin, and SYNAPTOSOMAL-ASSOCIATED PROTEIN 25. Mutations in the Brn-3c gene have been associated with DEAFNESS.
Preferred term Transcription Factor Brn-3C
Entry term(s) Brn 3c Transcription Factor
Brn-3C, Transcription Factor
Brn-3c Transcription Factor
POU Domain, Class 4, Transcription Factor 3
Pou4f3 Transcription Factor
Transcription Factor Brn 3C
Transcription Factor, Brn-3c
Transcription Factor, Pou4f3



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