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Descriptor English: POU Domain Factors
Descriptor Spanish: Factores del Dominio POU
Descriptor factores con dominios POU
Scope note: Familia de factores de transcripción caracterizados por la presencia de dominios de unión al ADN bipartitos, denominados dominios POU. Los dominios POU contienen dos subdominios, un dominio POU específico y un homeodominio POU. El dominio POU originalmente se identificó como una región de aproximadamente 150 aminoácidos compartidos entre Pit-1, Oct-1 y Oct-2 y factores de transcripción Unc-86.
Descriptor Portuguese: Fatores do Domínio POU
Descriptor French: Facteurs de transcription à domaine POU
Entry term(s): POU Proteins
POU, Transcription Factor
Pit Oct Unc Proteins
Pit-Oct-Unc Proteins
Transcription Factor POU
Tree number(s): D12.776.260.655
D12.776.930.710
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050809
Scope note: A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; TRANSCRIPTION FACTOR POU was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1992-2004
History Note: 2006(1992)
DeCS ID: 51034
Unique ID: D050809
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/06/29
POU Domain Factors - Preferred
Concept UI M0208075
Scope note A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
Preferred term POU Domain Factors
Entry term(s) POU Proteins
POU, Transcription Factor
Pit Oct Unc Proteins
Pit-Oct-Unc Proteins
Transcription Factor POU



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