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Descriptor English: Ternary Complex Factors
Descriptor Spanish: Factores Complejos Ternarios
Descriptor factores complejos ternarios
Scope note: Subclase de proteínas protoncogénicas c-ets que en un principio se describieron por su capacidad de unirse al ADN cuando se asociaban a otras proteínas reguladoras, como el FACTOR DE RESPUESTA SÉRICA. Contienen un dominio ets aminoterminal que se une al ADN junto con un dominio localmente centralizado en el FACTOR DE RESPUESTA SÉRICA y un dominio carboxi-terminal de activación de cinasa map. Este tipo de proteínas desempeñan una función importante en la regulación transcripcional de la SEÑALIZACIÓN INTRACELULAR DE PÉPTIDOS Y PROTEÍNAS.
Descriptor Portuguese: Fatores de Complexo Ternário
Descriptor French: Facteurs du complexe ternaire
Entry term(s): Complex Factors, Ternary
Complex Proteins, Ternary
Ternary Complex Proteins
Ternary Complex Transcription Factors
Tree number(s): D12.776.260.665.600
D12.776.624.664.700.175.600
D12.776.930.720.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050801
Scope note: A subclass of c-ets proto-oncogene proteins that were first described by their property of binding to DNA when associated with other regulatory proteins such as SERUM RESPONSE FACTOR. They contain an amino-terminal ets domain that binds to DNA along with centrally located SERUM RESPONSE FACTOR interacting domain, and carboxy-terminal map kinase activation domains. They play an important role in transcriptional regulation by INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006
History Note: 2006
DeCS ID: 51050
Unique ID: D050801
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/06/29
Ternary Complex Factors - Preferred
Concept UI M0477929
Scope note A subclass of c-ets proto-oncogene proteins that were first described by their property of binding to DNA when associated with other regulatory proteins such as SERUM RESPONSE FACTOR. They contain an amino-terminal ets domain that binds to DNA along with centrally located SERUM RESPONSE FACTOR interacting domain, and carboxy-terminal map kinase activation domains. They play an important role in transcriptional regulation by INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
Preferred term Ternary Complex Factors
Entry term(s) Complex Factors, Ternary
Complex Proteins, Ternary
Ternary Complex Proteins
Ternary Complex Transcription Factors



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