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Descriptor English: Core Binding Factor beta Subunit
Descriptor Spanish: Subunidad beta del Factor de Unión al Sitio Principal
Descriptor subunidad beta del factor de unión central
Entry term(s) betaproteína del CBF
proteína beta del CBF
proteína beta del factor de unión al sitio principal
proteína beta del factor de unión central
subunidad beta del CBF
Scope note: Factor de transcripción sin capacidad de reconocimiento de secuencias de ADN, que es una subunidad del factor de unión al sitio principal. Forma complejos heterodiméricos con las SUBUNIDADES ALFA DEL FACTOR DE UNIÓN AL SITIO PRINCIPAL, y regula la TRANSCRIPCIÓN de diversos GENES involucrados principalmente en la DIFERENCIACIÓN CELULAR y en la progresión del CICLO CELULAR.
Descriptor Portuguese: Subunidade beta de Fator de Ligação ao Core
Descriptor French: Sous-unités bêta du facteur CBF
Entry term(s): CBFB Protein
Core Binding Factor beta
Core Binding Factor beta Protein
Polyomavirus Enhancer Binding Protein 2, beta Subunit
Tree number(s): D12.776.930.155.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050658
Scope note: A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodimeric complexes with CORE BINDING FACTOR ALPHA SUBUNITS, and regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1987-2005)
Transcription Factors (1987-2005)
Public MeSH Note: 2006; CORE BINDING FACTOR BETA & CBFB PROTEIN were indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1987-2005
History Note: 2006(1987)
DeCS ID: 51179
Unique ID: D050658
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2005/08/03
Core Binding Factor beta Subunit - Preferred
Concept UI M0477050
Scope note A non-DNA binding transcription factor that is a subunit of core binding factor. It forms heterodimeric complexes with CORE BINDING FACTOR ALPHA SUBUNITS, and regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.
Preferred term Core Binding Factor beta Subunit
Entry term(s) CBFB Protein
Core Binding Factor beta
Core Binding Factor beta Protein
Polyomavirus Enhancer Binding Protein 2, beta Subunit



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