| Descriptor English: | Core Binding Factors | ||||||
| Descriptor Spanish: |
Factores de Unión al Sitio Principal
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| Descriptor Portuguese: | Fatores de Ligação ao Core | ||||||
| Descriptor French: | Facteurs de transcription CBF | ||||||
| Entry term(s): |
Binding Factors, Core Core Binding Factor Core-Binding Factor Factors, Core Binding PEBP2 Transcription Factor Polyomavirus Enhancer Binding Protein 2 Transcription Factor, PEBP2 |
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| Tree number(s): |
D12.776.930.155 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050660 | ||||||
| Scope note: | Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression. |
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| Annotation: | see SCR for organism-specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Neoplasm Proteins (1997-2005) Transcription Factors (1997-2005) |
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| Public MeSH Note: | 2006; CORE-BINDING FACTOR was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1997-2005 |
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| History Note: | 2006(1997) |
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| DeCS ID: | 51174 | ||||||
| Unique ID: | D050660 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2005/08/03 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Core Binding Factors
- Preferred
| Concept UI |
M0211900 |
| Scope note | Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression. |
| Preferred term | Core Binding Factors |
| Entry term(s) |
Binding Factors, Core Core Binding Factor Core-Binding Factor Factors, Core Binding PEBP2 Transcription Factor Polyomavirus Enhancer Binding Protein 2 Transcription Factor, PEBP2 |
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