Descriptor English: | Metabolic Detoxication, Phase II | ||||||
Descriptor Spanish: |
Fase II de la Desintoxicación Metabólica
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Descriptor Portuguese: | Desintoxicação Metabólica Fase II | ||||||
Descriptor French: | Détoxication de phase II | ||||||
Entry term(s): |
Conjugative Metabolic Detoxication Conjugative Metabolic Detoxications Detoxication, Conjugative Metabolic Detoxications, Conjugative Metabolic Detoxification, Phase II Detoxifications, Phase II Metabolic Detoxication, Conjugative Metabolic Detoxications, Conjugative Metabolic Detoxification, Phase II Phase II Detoxification Phase II Detoxifications |
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Tree number(s): |
G03.171.450.750 G03.787.225.450.750 G07.690.725.225.450.750 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050217 | ||||||
Scope note: | The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products. |
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Allowable Qualifiers: |
EH ethnology GE genetics IM immunology PH physiology RE radiation effects |
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Public MeSH Note: | 2006 |
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History Note: | 2006 |
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Entry Version: | METAB DETOX PHASE II |
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Related: |
Antioxidant Response Elements
MeSH Protein Processing, Post-Translational MeSH | ||||||
DeCS ID: | 51247 | ||||||
Unique ID: | D050217 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2006/01/01 | ||||||
Date of Entry: | 2005/06/30 | ||||||
Revision Date: | 2016/06/30 |
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PHENOMENA AND PROCESSES
Metabolism [G03]Metabolism -
PHENOMENA AND PROCESSES
Metabolism [G03]Metabolism -
PHENOMENA AND PROCESSES
Physiological Phenomena [G07]Physiological Phenomena
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Metabolic Detoxication, Phase II
- Preferred
Concept UI |
M0473296 |
Scope note | The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products. |
Preferred term | Metabolic Detoxication, Phase II |
Entry term(s) |
Conjugative Metabolic Detoxication Conjugative Metabolic Detoxications Detoxication, Conjugative Metabolic Detoxications, Conjugative Metabolic Detoxification, Phase II Detoxifications, Phase II Metabolic Detoxication, Conjugative Metabolic Detoxications, Conjugative Metabolic Detoxification, Phase II Phase II Detoxification Phase II Detoxifications |
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