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Descriptor English: Biotransformation
Descriptor Spanish: Biotransformación
Descriptor biotransformación
Scope note: Alteración química de una sustancia exógena mediante un sistema biológico. La alteración puede inactivar el compuesto o puede dar lugar a la producción de un metabolito activo a partir de un compuesto previo inactivo. Las alteraciones pueden dividirse en FASE I DE DESINTOXICACIÓN METABÓLICA y FASE II DE DESINTOXICACIÓN METABÓLICA.
Descriptor Portuguese: Biotransformação
Descriptor French: Biotransformation
Tree number(s): G03.171
G03.787.225
G07.690.725.225
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001711
Scope note: The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
Annotation: restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab; do not confuse with BIODEGRADATION, ENVIRONMENTAL
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 70
History Note: 70(66)
DeCS ID: 23169
Unique ID: D001711
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1970/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/02
Biotransformation - Preferred
Concept UI M0002566
Scope note The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
Preferred term Biotransformation



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