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Descriptor English: Caspase 3
Descriptor Spanish: Caspasa 3
Descriptor caspasa 3
Entry term(s) CASP3
CPP32
apopaína
proteína yama
Scope note: Caspasa de prodominio corto con papel efector en la APOPTOSIS. Es activada por CASPASAS INICIADORAS como la CASPASA 9. Existen diversas isoformas de esta proteína debido a las múltiples alternativas de corte y empalme de su ARN MENSAJERO.
Descriptor Portuguese: Caspase 3
Descriptor French: Caspase-3
Entry term(s): Apopain
CASP3
Caspase-3
Pro Caspase 3
Pro-Caspase-3
Procaspase 3
Procaspase-3
Tree number(s): D08.811.277.656.262.500.126.350.300
D08.811.277.656.300.200.126.350.300
D12.776.476.075.405.350.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053148
Scope note: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Caspase Inhibitors
Registry Number: EC 3.4.22.-
Public MeSH Note: 2007; CASPASE 3 was indexed under CASPASES 1999-2005 & under CYSTEINE PROTEINASES 1995-1998
History Note: 2007(1995)
DeCS ID: 52221
Unique ID: D053148
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/11/23
Caspase 3 - Preferred
Concept UI M0239778
Scope note A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Preferred term Caspase 3
Entry term(s) Apopain
CASP3
Caspase-3
Procaspase-3 - Narrower
Concept UI M0296643
Preferred term Procaspase-3
Entry term(s) Pro Caspase 3
Pro-Caspase-3
Procaspase 3



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