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Descriptor English: Caspases, Effector
Descriptor Spanish: Caspasas Efectoras
Descriptor caspasas efectoras
Scope note: Subclase de caspasas que contienen regiones prodominio cortas. Son activadas por la acción proteolítica de las CASPASAS INICIADORAS. Una vez activadas escinden diversos sustratos que causan la APOPTOSIS.
Descriptor Portuguese: Caspases Efetoras
Descriptor French: Caspases effectrices
Entry term(s): Effector Caspases
Tree number(s): D08.811.277.656.262.500.126.350
D08.811.277.656.300.200.126.350
D12.776.476.075.405.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053470
Scope note: A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic action of INITIATOR CASPASES. Once activated they cleave a variety of substrates that cause APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Caspase Inhibitors
Registry Number: EC 3.4.22.-
Previous Indexing: Caspases (1999-2006)
Cysteine Proteinases (1997-1998)
Public MeSH Note: 2007
History Note: 2007
DeCS ID: 52220
Unique ID: D053470
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/11/23
Caspases, Effector - Preferred
Concept UI M0491613
Scope note A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic action of INITIATOR CASPASES. Once activated they cleave a variety of substrates that cause APOPTOSIS.
Preferred term Caspases, Effector
Entry term(s) Effector Caspases



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