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Descriptor English: Matrix Metalloproteinase 16
Descriptor Spanish: Metaloproteinasa 16 de la Matriz
Descriptor metaloproteinasa 16 de la matriz
Entry term(s) metaloproteinasa-16 de la matriz
Scope note: Metaloproteinasa de la matriz con dominio transmembrana. Es sintetizada como un zimógeno inactivo que es activado por la acción de las PROPROTEÍNA CONVERTASAS. La metaloproteinasa de la matriz 16 interviene directamente en la escisión de proteínas pericelulares. Además, funciona indirectamente activando enzimáticamente la forma proproteína de otras METALOPROTEINASAS como el zimógeno de la MATRIZ.
Descriptor Portuguese: Metaloproteinase 16 da Matriz
Descriptor French: Matrix metalloproteinase 16
Entry term(s): MMP 16 Metalloproteinase
MMP X2 Protein
MMP-16 Metalloproteinase
MMP-X2 Protein
MMP16 Metalloproteinase
MT3 Matrix Metalloproteinase
MT3-MMP
MT3-Matrix Metalloproteinase
Matrix Metalloproteinase, Membrane-Type-3
Membrane Type 3 Matrix Metalloproteinase
Membrane Type Matrix Metalloproteinase 3
Membrane-Type 3 Matrix Metalloproteinase
Membrane-Type Matrix Metalloproteinase 3
Membrane-Type-3 Matrix Metalloproteinase
Metalloproteinase, MMP-16
Metalloproteinase, MMP16
Metalloproteinase, Membrane-Type-3 Matrix
Tree number(s): D08.811.277.656.300.480.525.300.600
D08.811.277.656.675.374.525.300.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053513
Scope note: A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Registry Number: EC 3.4.24.-
Public MeSH Note: 2007; MATRIX METALLOPROTEINASE 16 was indexed under MATRIX METALLOPROTEINASES 2006 & under METALLOENDOPEPTIDASES 2005
History Note: 2007(2005)
DeCS ID: 52235
Unique ID: D053513
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2012/07/03
Matrix Metalloproteinase 16 - Preferred
Concept UI M0284099
Scope note A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.
Preferred term Matrix Metalloproteinase 16
Entry term(s) MMP 16 Metalloproteinase
MMP X2 Protein
MMP-16 Metalloproteinase
MMP-X2 Protein
MMP16 Metalloproteinase
MT3 Matrix Metalloproteinase
MT3-MMP
MT3-Matrix Metalloproteinase
Matrix Metalloproteinase, Membrane-Type-3
Membrane Type 3 Matrix Metalloproteinase
Membrane Type Matrix Metalloproteinase 3
Membrane-Type 3 Matrix Metalloproteinase
Membrane-Type Matrix Metalloproteinase 3
Membrane-Type-3 Matrix Metalloproteinase
Metalloproteinase, MMP-16
Metalloproteinase, MMP16
Metalloproteinase, Membrane-Type-3 Matrix



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