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Descriptor English: Apoprotein(a)
Descriptor Spanish: Apoproteína(a)
Descriptor apoproteína(a)
Entry term(s) apolipoproteína Lp(a)
Scope note: Proteína de gran tamaño y muy glicosilada constituyente de la LIPOPROTEÍNA (A). Tiene una muy escasa afinidad por los lípidos pero forma una unión disulfuro con la APOLIPOPROTEÍNA B100. La apoproteína (a) tiene actividad SERINA PROTEINASA y puede tener tamaños diferentes, desde 400 a 800 kDa. Es homóloga al PLASMINÓGENO y se sabe que modula la TROMBOSIS y la FIBRINOLISIS.
Descriptor Portuguese: Apoproteína(a)
Descriptor French: Apoprotéine A
Entry term(s): Antiangiogenic AK38 Protein
Apo Lp(a)
Apolipoprotein (a)
Apolipoprotein Lp(a)
Apolipoprotein Lp(a+)
Apolipoprotein(a)
Apoprotein (a)
Protein, Antiangiogenic AK38
Tree number(s): D10.532.350.500
D12.776.521.400.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053241
Scope note: A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
Annotation: do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.-
Previous Indexing: Apolipoproteins (1977-1993)
Apolipoproteins A (1982-2006)
Apoproteins (1978-2004)
Public MeSH Note: 2007; see APOLIPOPROTEINS A 1988-2006; APOLIPOPROTEIN LP(A+) was indexed under APOLIPOPROTEINS & LIPOPROTEIN(A) 1986-2006
History Note: 2007 (1986); use APOLIPOPROTEINS A 1988-2006
DeCS ID: 52270
Unique ID: D053241
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/20
Apoprotein(a) - Preferred
Concept UI M0001595
Scope note A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
Preferred term Apoprotein(a)
Entry term(s) Antiangiogenic AK38 Protein
Apo Lp(a)
Apolipoprotein (a)
Apolipoprotein Lp(a)
Apolipoprotein Lp(a+)
Apolipoprotein(a)
Apoprotein (a)
Protein, Antiangiogenic AK38



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