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Descriptor English: Epithelial Sodium Channels
Descriptor Spanish: Canales Epiteliales de Sodio
Descriptor canales del sodio epiteliales
Entry term(s) canal del sodio epitelial
canales epiteliales del sodio
canales iónicos del sodio epitelial
Scope note: Canales de sodio que se encuentran en las CÉLULAS EPITELIALES que reabsorben sodio y tapizan la NEFRONA distal, el COLON distal, los CONDUCTOS SALIVALES, las GLÁNDULAS SUDORÍPARAS y el PULMÓN. Son sensibles a la AMILORIDA y tienen un papel crítico en el control del equilibrio del sodio, en el VOLUMEN SANGUÍNEO y en la PRESIÓN ARTERIAL.
Descriptor Portuguese: Canais Epiteliais de Sódio
Descriptor French: Canaux sodium épithéliaux
Entry term(s): ENaC (Epithelial Na+ Channel)
ENaC alpha
ENaC beta
ENaC delta
ENaC gamma
Epithelial Amiloride Sensitive Sodium Channel
Epithelial Amiloride-Sensitive Sodium Channel
Epithelial Sodium Channel
Epithelial Sodium Channel, alpha Subunit
Epithelial Sodium Channel, beta Subunit
Epithelial Sodium Channel, delta Subunit
Epithelial Sodium Channel, gamma Subunit
Epithelial Sodium Ion Channels
SCNN1 alpha Subunit
SCNN1 beta Subunit
SCNN1 delta Subunit
SCNN1 gamma Subunit
Sodium Channel, Epithelial
Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit
Sodium Channels, Epithelial
alpha Subunit, SCNN1
Tree number(s): D12.776.157.530.400.875.200
D12.776.543.550.450.875.200
D12.776.543.585.400.875.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053503
Scope note: Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Epithelial Sodium Channel Blockers
agonists:Epithelial Sodium Channel Agonists
Public MeSH Note: 2013; see EPITHELIAL SODIUM CHANNEL 2007-2012; EPITHELIAL SODIUM CHANNEL was indexed under SODIUM CHANNELS 1995-2006
History Note: 2013(1995)
DeCS ID: 52323
Unique ID: D053503
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/07/01
Epithelial Sodium Channels - Preferred
Concept UI M0254795
Scope note Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.
Preferred term Epithelial Sodium Channels
Entry term(s) ENaC (Epithelial Na+ Channel)
Epithelial Amiloride Sensitive Sodium Channel
Epithelial Amiloride-Sensitive Sodium Channel
Epithelial Sodium Channel
Epithelial Sodium Ion Channels
Sodium Channel, Epithelial
Sodium Channels, Epithelial
Epithelial Sodium Channel, gamma Subunit - Narrower
Concept UI M0484146
Preferred term Epithelial Sodium Channel, gamma Subunit
Entry term(s) ENaC gamma
SCNN1 gamma Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit
Epithelial Sodium Channel, delta Subunit - Narrower
Concept UI M0484148
Preferred term Epithelial Sodium Channel, delta Subunit
Entry term(s) ENaC delta
SCNN1 delta Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit
Epithelial Sodium Channel, alpha Subunit - Narrower
Concept UI M0484144
Preferred term Epithelial Sodium Channel, alpha Subunit
Entry term(s) ENaC alpha
SCNN1 alpha Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit
alpha Subunit, SCNN1
Epithelial Sodium Channel, beta Subunit - Narrower
Concept UI M0484145
Preferred term Epithelial Sodium Channel, beta Subunit
Entry term(s) ENaC beta
SCNN1 beta Subunit
Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit



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