| Descriptor English: | Voltage-Gated Sodium Channels | ||||||
| Descriptor Spanish: |
Canales de Sodio Activados por Voltaje
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| Descriptor Portuguese: | Canais de Sódio Disparados por Voltagem | ||||||
| Descriptor French: | Canaux sodiques voltage-dépendants | ||||||
| Entry term(s): |
Channel, Voltage-Gated Sodium Channels, Voltage-Gated Sodium Sodium Channel, Voltage-Gated Sodium Channels, Voltage Gated Sodium Channels, Voltage-Gated Voltage Gated Sodium Channel Voltage Gated Sodium Channels Voltage-Gated Sodium Channel |
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| Tree number(s): |
D12.776.157.530.400.875.750 D12.776.543.550.450.875.750 D12.776.543.585.400.875.750 D12.776.631.960 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D061566 | ||||||
| Scope note: | A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity. |
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| Annotation: | general or unspecified; prefer specifics |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
agonists:Voltage-Gated Sodium Channel Agonists |
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| Previous Indexing: |
Sodium Channels (1989-2012) |
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| Public MeSH Note: | 2013 |
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| History Note: | 2013 |
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| DeCS ID: | 54946 | ||||||
| Unique ID: | D061566 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2013/01/01 | ||||||
| Date of Entry: | 2012/07/03 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Voltage-Gated Sodium Channels
- Preferred
| Concept UI |
M0559314 |
| Scope note | A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity. |
| Preferred term | Voltage-Gated Sodium Channels |
| Entry term(s) |
Channel, Voltage-Gated Sodium Channels, Voltage-Gated Sodium Sodium Channel, Voltage-Gated Sodium Channels, Voltage Gated Sodium Channels, Voltage-Gated Voltage Gated Sodium Channel Voltage Gated Sodium Channels Voltage-Gated Sodium Channel |
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