| Descriptor English: | Acid Sensing Ion Channels | ||||||
| Descriptor Spanish: |
Canales Iónicos Sensibles al Ácido
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| Descriptor Portuguese: | Canais Iônicos Sensíveis a Ácido | ||||||
| Descriptor French: | Canaux ioniques sensibles à l'acidité | ||||||
| Entry term(s): |
ASIC Channel Acid Sensing Ion Channel Acid-Sensing Ion Channel Acid-Sensing Ion Channels Channel, Acid-Sensing Ion Channel, Proton-Gated Sodium Ion Channel, Acid-Sensing Proton Gated Sodium Channel Proton Gated Sodium Channels Proton-Gated Sodium Channel Proton-Gated Sodium Channels Sodium Channel, Proton-Gated Sodium Channels, Proton-Gated |
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| Tree number(s): |
D12.776.157.530.400.875.050 D12.776.543.550.450.875.050 D12.776.543.585.400.875.050 D12.776.631.024 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D062565 | ||||||
| Scope note: | A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Acid Sensing Ion Channel Blockers
agonists:Sodium Channel Agonists |
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| Previous Indexing: |
Sodium Channels (1988-2012) |
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| Public MeSH Note: | 2013; ASIC CHANNEL (now ACID SENSING ION CHANNELS) was indexed under NERVE TISSUE PROTEINS and SODIUM CHANNELS 2009-2012, and under MEMBRANE PROTEINS 1997-2008 |
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| History Note: | 2013 |
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| DeCS ID: | 54944 | ||||||
| Unique ID: | D062565 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2013/01/01 | ||||||
| Date of Entry: | 2012/07/03 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Acid Sensing Ion Channels
- Preferred
| Concept UI |
M0568648 |
| Scope note | A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions. |
| Preferred term | Acid Sensing Ion Channels |
| Entry term(s) |
ASIC Channel Acid Sensing Ion Channel Acid-Sensing Ion Channel Acid-Sensing Ion Channels Channel, Acid-Sensing Ion Channel, Proton-Gated Sodium Ion Channel, Acid-Sensing Proton Gated Sodium Channel Proton Gated Sodium Channels Proton-Gated Sodium Channel Proton-Gated Sodium Channels Sodium Channel, Proton-Gated Sodium Channels, Proton-Gated |
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