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Descriptor English: Group IV Phospholipases A2
Descriptor Spanish: Fosfolipasas A2 Grupo IV
Descriptor fosfolipasas A2 del grupo IV
Scope note: Grupo de fosfolipasas A2 citosólicas que desempeña un importante papel en la liberación de ÁCIDO ARAQUIDÓNICO libre, que a su vez es metabolizado por la vía de la CICLOOXIGENASA dando lugar a PROSTAGLANDINAS y por la vía de la 5-LIPOOXIGENASA para dar lugar a LEUCOTRIENOS.
Descriptor Portuguese: Fosfolipases A2 do Grupo IV
Descriptor French: Group IV phospholipases A2
Entry term(s): Cytosolic Phospholipase A2 alpha
Cytosolic Phospholipase A2 beta
Cytosolic Phospholipase A2 delta
Cytosolic Phospholipase A2 epsilon
Cytosolic Phospholipase A2 gamma
Group IV Cytosolic Phospholipase A2
Group IVA Phospholipase A2
Group IVA Phospholipases A2
Group IVB Phospholipase A2
Group IVB Phospholipases A2
Group IVC Phospholipase A2
Group IVC Phospholipases A2
Group IVD Phospholipase A2
Group IVD Phospholipases A2
Group IVE Phospholipase A2
Group IVE Phospholipases A2
Group IVF Phospholipase A2
Group IVF Phospholipases A2
PLA(2)-IV
PLA2-IV
Phospholipase A(2)alpha
Phospholipase A2 Group IVA
Phospholipase A2 IV
Phospholipase A2 alpha
Phospholipase A2 beta
Phospholipase A2 gamma
Phospholipase A2, Group IVB
Phospholipase A2, Group IVC
Phospholipase A2, Group IVD
Phospholipase A2, Group IVE
Phospholipase A2, Group IVF
Phospholipase A2-alpha
Phospholipase A2-beta
Phospholipase A2-gamma
Phospholipases A2, Group IV
cPLA2 alpha
cPLA2 gamma
cPLA2-alpha
cPLA2-gamma
Tree number(s): D08.811.277.352.100.680.750.937.625.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054513
Scope note: A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.1.4
Public MeSH Note: 2008; GROUP IV PHOSPHOLIPASE A2 was indexed under to PHOSPHOLIPASES A 1997-2007; PHOSPHOLIPASE A2-ALPHA was indexed under PHOSPHOLIPASES A 2000-2007; PHOSPHOLIPASE A2-BETA was indexed under PHOSPHOLIPASES A 1999-2007; PHOSPHOLIPASE A2-GAMMA was indexed under PHOSPHOLIPASES A 1998-2007
History Note: 2008(1997)
DeCS ID: 52666
Unique ID: D054513
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Group IV Phospholipases A2 - Preferred
Concept UI M0222411
Scope note A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
Preferred term Group IV Phospholipases A2
Entry term(s) Group IV Cytosolic Phospholipase A2
PLA(2)-IV
PLA2-IV
Phospholipase A2 IV
Phospholipases A2, Group IV
Group IVB Phospholipase A2 - Narrower
Concept UI M0505798
Preferred term Group IVB Phospholipase A2
Entry term(s) Cytosolic Phospholipase A2 beta
Group IVB Phospholipases A2
Phospholipase A2 beta
Phospholipase A2, Group IVB
Phospholipase A2-beta
Group IVC Phospholipase A2 - Narrower
Concept UI M0505799
Preferred term Group IVC Phospholipase A2
Entry term(s) Cytosolic Phospholipase A2 gamma
Group IVC Phospholipases A2
Phospholipase A2 gamma
Phospholipase A2, Group IVC
Phospholipase A2-gamma
cPLA2 gamma
cPLA2-gamma
Group IVE Phospholipase A2 - Narrower
Concept UI M0505804
Preferred term Group IVE Phospholipase A2
Entry term(s) Cytosolic Phospholipase A2 epsilon
Group IVE Phospholipases A2
Phospholipase A2, Group IVE
Group IVF Phospholipase A2 - Narrower
Concept UI M0505805
Preferred term Group IVF Phospholipase A2
Entry term(s) Group IVF Phospholipases A2
Phospholipase A2, Group IVF
Group IVA Phospholipase A2 - Narrower
Concept UI M0505797
Preferred term Group IVA Phospholipase A2
Entry term(s) Cytosolic Phospholipase A2 alpha
Group IVA Phospholipases A2
Phospholipase A(2)alpha
Phospholipase A2 Group IVA
Phospholipase A2 alpha
Phospholipase A2-alpha
cPLA2 alpha
cPLA2-alpha
Group IVD Phospholipase A2 - Narrower
Concept UI M0505801
Preferred term Group IVD Phospholipase A2
Entry term(s) Cytosolic Phospholipase A2 delta
Group IVD Phospholipases A2
Phospholipase A2, Group IVD



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