Descriptor English: | Nicotinamide Phosphoribosyltransferase | ||||||
Descriptor Spanish: |
Nicotinamida Fosforribosiltransferasa
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Descriptor Portuguese: | Nicotinamida Fosforribosiltransferase | ||||||
Descriptor French: | Nicotinamide phosphoribosyltransferase | ||||||
Entry term(s): |
Colony-Enhancing Factor, Pre-B-Cell NAMPT Protein NAmPRTase NMN Pyrophosphorylase Phosphoribosyltransferase, Nicotinamide Pre B Cell Colony Enhancing Factor Pre-B-Cell Colony-Enhancing Factor Visfatin |
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Tree number(s): |
D08.811.913.400.725.575 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054409 | ||||||
Scope note: | An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.4.2.12 | ||||||
Previous Indexing: |
Pentosyltransferases (1972-2007) |
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Public MeSH Note: | 2008; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE was indexed under PENTOSYLTRANSFERASES 1982-2007 |
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History Note: | 2008 (1982) |
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DeCS ID: | 52725 | ||||||
Unique ID: | D054409 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2008/01/01 | ||||||
Date of Entry: | 2007/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Nicotinamide Phosphoribosyltransferase
- Preferred
Concept UI |
M0103184 |
Scope note | An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). |
Preferred term | Nicotinamide Phosphoribosyltransferase |
Entry term(s) |
Colony-Enhancing Factor, Pre-B-Cell NAMPT Protein NAmPRTase NMN Pyrophosphorylase Phosphoribosyltransferase, Nicotinamide Pre B Cell Colony Enhancing Factor Pre-B-Cell Colony-Enhancing Factor Visfatin |
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