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Descriptor English: Elongation Factor 2 Kinase
Descriptor Spanish: Quinasa del Factor 2 de Elongación
Descriptor cinasa del factor 2 de elongación
Entry term(s) proteína cinasa III dependiente de calmodulina
proteína cinasa tipo 3 dependiente de calcio-calmodulina
proteína quinasa III dependiente de calmodulina
proteína quinasa tipo 3 dependiente de calcio-calmodulina
Scope note: Subtipo monomérico de proteína cinasa dependiente de calcio-calmodulina que de modo específico fosforila el FACTOR 2 DE ELONGACIÓN PEPTÍDICA. La enzima carece de dominio de activación fosforilable que pueda responder a la PROTEÍNA CINASA CINASA DEPENDIENTE DE CALCIO-CALMODULINA; sin embargo, está regulada por fosforilación por la PROTEÍNA CINASA A y por autofosforilación intramolecular.
Descriptor Portuguese: Quinase do Fator 2 de Elongação
Descriptor French: Elongation Factor 2 Kinase
Entry term(s): CAM Kinase III
Calcium Calmodulin Dependent Protein Kinase Type 3
Calcium-Calmodulin-Dependent Protein Kinase Type 3
Calmodulin Dependent Protein Kinase III
Calmodulin-Dependent Protein Kinase III
Cam PK III
E 2 Kinase
E-2 Kinase
EF 2 Kinase
EF-2 Kinase
Eukaryotic Elongation Factor 2 Kinase
Eukaryotic Elongation Factor-2 Kinase
Kinase CPK3, Protein
Kinase, EF-2
Protein Kinase CPK3
eEF 2 Specific Ca and Calmodulin Dependent Protein Kinase III
eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III
Tree number(s): D08.811.913.696.620.682.700.125.425
D12.776.476.563.125.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054736
Scope note: A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.20
Public MeSH Note: 2008; CALMODULIN-DEPENDENT PROTEIN KINASE III (now ELONGATION FACTOR 2 KINASE) was indexed under CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES 1987-2007
History Note: 2008(1987)
DeCS ID: 52731
Unique ID: D054736
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2016/06/29
Elongation Factor 2 Kinase - Preferred
Concept UI M0150644
Scope note A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation.
Preferred term Elongation Factor 2 Kinase
Entry term(s) CAM Kinase III
Calcium Calmodulin Dependent Protein Kinase Type 3
Calcium-Calmodulin-Dependent Protein Kinase Type 3
Calmodulin Dependent Protein Kinase III
Calmodulin-Dependent Protein Kinase III
Cam PK III
E 2 Kinase
E-2 Kinase
EF 2 Kinase
EF-2 Kinase
Eukaryotic Elongation Factor 2 Kinase
Eukaryotic Elongation Factor-2 Kinase
Kinase CPK3, Protein
Kinase, EF-2
Protein Kinase CPK3
eEF 2 Specific Ca and Calmodulin Dependent Protein Kinase III
eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III



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