| Descriptor English: | Bone Morphogenetic Protein 1 | ||||||
| Descriptor Spanish: |
Proteína Morfogenética Ósea 1
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| Descriptor Portuguese: | Proteína Morfogenética Óssea 1 | ||||||
| Descriptor French: | Protéine morphogénétique osseuse de type 1 | ||||||
| Entry term(s): |
Procollagen C Endopeptidase Procollagen C-Endopeptidase |
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| Tree number(s): |
D08.811.277.656.300.480.525.700.049 D08.811.277.656.675.374.525.700.900.500 D12.644.276.954.200.100 D12.776.467.836.049 D12.776.467.942.200.100 D12.776.467.948.500 D23.529.942.200.100 D23.529.948.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D055395 | ||||||
| Scope note: | A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.4.24.19 | ||||||
| Public MeSH Note: | 2009; BONE MORPHOGENETIC PROTEIN 1 was inedxed under METALLOENDPEPTIDASES & BONE MORPHOGENETIC PROTEINS 1996-2008, under PEPTIDE PEPTIDOHYDROLASES 1978-1995, & under PROCOLLAGEN 1978-1982 |
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| History Note: | 2009(1978) |
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| DeCS ID: | 53118 | ||||||
| Unique ID: | D055395 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2009/01/01 | ||||||
| Date of Entry: | 2008/07/08 | ||||||
| Revision Date: | 2016/04/18 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Bone Morphogenetic Protein 1
- Preferred
| Concept UI |
M0517439 |
| Scope note | A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS. |
| Preferred term | Bone Morphogenetic Protein 1 |
| Entry term(s) |
Procollagen C Endopeptidase Procollagen C-Endopeptidase |
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