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Descriptor English: Bone Morphogenetic Protein 5
Descriptor Spanish: Proteína Morfogenética Ósea 5
Descriptor proteína morfogenética ósea 5
Entry term(s) proteínas morfogenéticas de hueso 5
Scope note: Proteína morfogenética ósea que participa en la formación del CARTÍLAGO. Es un potente regulador del crecimiento de los CONDROCITOS y de la síntesis de las proteínas de la matriz del cartílago. Su papel en la formación del cartílago puede demostrarse en el RATÓN, en el que mutaciones genéticas que producen la pérdida de función de la proteína 5 morfogenética ósea dan lugar a la formación de pequeñas orejas malformadas. 
Descriptor Portuguese: Proteína Morfogenética Óssea 5
Descriptor French: Protéine morphogénétique osseuse de type 5
Entry term(s): BMP-5
Tree number(s): D12.644.276.954.200.500
D12.776.467.942.200.500
D23.529.942.200.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055417
Scope note: A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2009; BONE MORPHOGENETIC PROTEIN 5 was indexed under BONE MORPHOGENETIC PROTEINS 1997-2008
History Note: 2009(1997)
DeCS ID: 53132
Unique ID: D055417
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Bone Morphogenetic Protein 5 - Preferred
Concept UI M0274551
Scope note A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.
Preferred term Bone Morphogenetic Protein 5
Entry term(s) BMP-5



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