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Descriptor English: Cell Cycle Checkpoints
Descriptor Spanish: Puntos de Control del Ciclo Celular
Descriptor puntos de comprobación del ciclo celular
Entry term(s) detención del ciclo celular
Scope note: "Sistemas de regulación de señalización que controlan la progresión del CICLO CELULAR. Aseguran de que la célula ha terminado, en el orden correcto y sin errores, todos los procesos necesarios para replicar el GENOMA y el CITOPLASMA, y se dividen por igual entre las dos células hijas. Si el entorno de las células no ha completado estos procesos o el ambiente no tiene los nutrientes y hormonas de crecimiento dispuestos, entonces las células se ven limitadas (o ""detenidas"") hasta que los procesos se ha completado y las condiciones de crecimiento son adecuadas."
Descriptor Portuguese: Pontos de Checagem do Ciclo Celular
Descriptor French: Points de contrôle du cycle cellulaire
Entry term(s): Arrest, Cell Cycle
Arrests, Cell Cycle
Cell Cycle Arrest
Cell Cycle Arrests
Cell Cycle Checkpoint
Cell Cycle Control
Cell Cycle Controls
Cell Cycle Transition Points
Cell Cycle-Transition Point
Cell Cycle-Transition Points
Checkpoint, Cell Cycle
Checkpoints, Cell Cycle
Control, Cell Cycle
Controls, Cell Cycle
Cycle-Transition Point, Cell
Point, Cell Cycle-Transition
Tree number(s): G04.144.109
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D059447
Scope note: Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Annotation: general; prefer specifics
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Cell Cycle or specifics(1989-2011)
Public MeSH Note: 2012
History Note: 2012
Related: Cell Cycle Proteins MeSH
Genes, cdc MeSH
DeCS ID: 54784
Unique ID: D059447
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2016/01/15
Cell Cycle Checkpoints - Preferred
Concept UI M0550145
Scope note Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.
Preferred term Cell Cycle Checkpoints
Entry term(s) Cell Cycle Checkpoint
Checkpoint, Cell Cycle
Checkpoints, Cell Cycle
Cell Cycle Transition Points - Related but not broader or narrower
Concept UI M0551545
Preferred term Cell Cycle Transition Points
Entry term(s) Cell Cycle-Transition Point
Cell Cycle-Transition Points
Cycle-Transition Point, Cell
Point, Cell Cycle-Transition
Cell Cycle Arrest - Related but not broader or narrower
Concept UI M0550147
Scope note The halting of progression of a cell through the CELL CYCLE when events in the CELL DIVISION process are not completed accurately or damage to cell components in the process are detected.
Preferred term Cell Cycle Arrest
Entry term(s) Arrest, Cell Cycle
Arrests, Cell Cycle
Cell Cycle Arrests
Cell Cycle Control - Related but not broader or narrower
Concept UI M0550146
Scope note Cellular mechanisms that ensure that all events occuring during specific times in the CELL CYCLE are completed and without mistakes prior to progression to the next phase of the cell cycle.
Preferred term Cell Cycle Control
Entry term(s) Cell Cycle Controls
Control, Cell Cycle
Controls, Cell Cycle



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