| Descriptor English: | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels | ||||||
| Descriptor Spanish: |
Canales Regulados por Nucleótidos Cíclicos Activados por Hiperpolarización
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| Descriptor Portuguese: | Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização | ||||||
| Descriptor French: | Canaux contrôlés par les nucléotides cycliques et activés par l'hyperpolarisation | ||||||
| Entry term(s): |
Cation Channel, Hyperpolarization-Activated Cation Channels, Ih Channel, HCN1 Channel, HCN2 Channel, HCN2 Potassium Channel, HCN3 Channel, HCN4 Channel, Hyperpolarization-Activated Cation Channels, HCN Pacemaker Channels, Ih Cation HCN Pacemaker Channels HCN1 Channel HCN2 Channel HCN2 Potassium Channel HCN3 Channel HCN4 Channel Hyperpolarization Activated Cation Channel Hyperpolarization Activated Cyclic Nucleotide Gated Channels Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2 Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4 Hyperpolarization Cyclic Nucleotide Gated Ion Channels Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1 Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3 Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4 Hyperpolarization Cyclic-Nucleotide Gated Ion Channels Hyperpolarization-Activated Cation Channel I(h) Cation Channels I(h) Channels Ih Cation Channels Pacemaker Channels, HCN Potassium Channel, HCN2 Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2 Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 |
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| Tree number(s): |
D12.776.157.530.400.368 D12.776.543.550.450.476 D12.776.543.585.400.476 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D064428 | ||||||
| Scope note: | A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Cyclic Nucleotide-Gated Cation Channels (2001-2013) |
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| Public MeSH Note: | 2014; see CYCLIC NUCLEOTIDE-GATED CATION CHANNELS 2009-2013; for HCN2 POTASSIUM CHANNEL see ION CHANNELS 2005-2013 and MUSCLE PROTEINS 1999-2005 |
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| History Note: | 2014 |
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| DeCS ID: | 55318 | ||||||
| Unique ID: | D064428 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2014/01/01 | ||||||
| Date of Entry: | 2013/07/08 | ||||||
| Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Preferred
HCN4 Channel
- Narrower
HCN3 Channel
- Narrower
HCN1 Channel
- Narrower
HCN2 Channel
- Narrower
| Concept UI |
M0507996 |
| Scope note | A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium. |
| Preferred term | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels |
| Entry term(s) |
Cation Channel, Hyperpolarization-Activated Cation Channels, Ih Channel, Hyperpolarization-Activated Cation Channels, HCN Pacemaker Channels, Ih Cation HCN Pacemaker Channels Hyperpolarization Activated Cation Channel Hyperpolarization Activated Cyclic Nucleotide Gated Channels Hyperpolarization Cyclic Nucleotide Gated Ion Channels Hyperpolarization Cyclic-Nucleotide Gated Ion Channels Hyperpolarization-Activated Cation Channel I(h) Cation Channels I(h) Channels Ih Cation Channels Pacemaker Channels, HCN |
| Concept UI |
M0581945 |
| Preferred term | HCN4 Channel |
| Entry term(s) |
Channel, HCN4 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4 Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4 |
| Concept UI |
M0581944 |
| Preferred term | HCN3 Channel |
| Entry term(s) |
Channel, HCN3 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3 Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3 |
| Concept UI |
M0581943 |
| Preferred term | HCN1 Channel |
| Entry term(s) |
Channel, HCN1 Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1 Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1 |
| Concept UI |
M0306107 |
| Preferred term | HCN2 Channel |
| Entry term(s) |
Channel, HCN2 Channel, HCN2 Potassium HCN2 Potassium Channel Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2 Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 Potassium Channel, HCN2 Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2 Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 |
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