| Descriptor English: | Transient Receptor Potential Channels | ||||||
| Descriptor Spanish: |
Canales de Potencial de Receptor Transitorio
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| Descriptor Portuguese: | Canais de Potencial de Receptor Transitório | ||||||
| Descriptor French: | Canaux cationiques TRP | ||||||
| Entry term(s): |
Cation Channel, TRP Cation Channels, TRP Channel, TRP Cation Channels, TRP Cation Membrane Proteins, TRP Proteins, TRP Membrane TRP Cation Channel TRP Cation Channels TRP Membrane Proteins Transient Receptor Potential Cation Channel Transient Receptor Potential Cation Channels Transient Receptor Potential Channel |
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| Tree number(s): |
D12.776.157.530.400.901 D12.776.543.585.400.901 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050051 | ||||||
| Scope note: | A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES. |
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| Annotation: | note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Calcium Channels (1989-2005) Ion Channels (1995-2005) |
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| Public MeSH Note: | 2006 |
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| History Note: | 2006 |
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| Entry Version: | TRANSIENT RECEPT POTENTIAL CHANNELS |
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| DeCS ID: | 50884 | ||||||
| Unique ID: | D050051 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Transient Receptor Potential Channels
- Preferred
| Concept UI |
M0472345 |
| Scope note | A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES. |
| Preferred term | Transient Receptor Potential Channels |
| Entry term(s) |
Cation Channel, TRP Cation Channels, TRP Channel, TRP Cation Channels, TRP Cation Membrane Proteins, TRP Proteins, TRP Membrane TRP Cation Channel TRP Cation Channels TRP Membrane Proteins Transient Receptor Potential Cation Channel Transient Receptor Potential Cation Channels Transient Receptor Potential Channel |
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