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Descriptor English: Gasdermins
Descriptor Spanish: Gasderminas
Descriptor gasderminas
Entry term(s) proteínas que contienen un dominio de gasdermina (GSDMDC) asociadas al cáncer
Scope note: Familia de proteínas efectoras formadoras de poros que causan permeabilización de la membrana y PIROPTOSIS. La piroptosis inducida por gasderminas desempeña un papel destacado en muchas ENFERMEDADES HEREDITARIAS y trastornos autoinflamatorios, así como en el CÁNCER.
Descriptor Portuguese: Gasderminas
Descriptor French: Gasdermines
Entry term(s): Cancer Associated Gasdermin-Domain Containing (GSDMDC) Proteins
Tree number(s): D12.776.157.530.400.353
D12.776.543.550.450.464
D12.776.543.585.400.464
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000094524
Scope note: A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2023
History Note: 2023
DeCS ID: 60255
Unique ID: D000094524
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2023/01/01
Date of Entry: 2022/07/08
Revision Date: 2022/07/08
Gasdermins - Preferred
Concept UI M000756051
Scope note A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.
Preferred term Gasdermins
Entry term(s) Cancer Associated Gasdermin-Domain Containing (GSDMDC) Proteins



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