Search
Descriptor English: NF-KappaB Inhibitor alpha
Descriptor Spanish: Inhibidor NF-kappaB alfa
Descriptor inhibidor alfa de NF-kappaB
Entry term(s) alfa IkappaB
alfaIkappaB
proteína MAD3 potenciadora de la unión al complejo mayor de histocompatibilidad
proteína alfa I-kappa B
proteína p40
Scope note: Proteína I-Kappa B que inhibe la actividad de los complejos diméricos NF-KAPPA B P50-REL. Secuestra el factor de transcripción NF-kappa B en forma de complejo inactivo en el citoplasma y previene la translocación nuclear de NF-kappaB y la unión al ADN.
Descriptor Portuguese: Inibidor de NF-kappaB alfa
Descriptor French: Inhibiteur alpha de NF-KappaB
Entry term(s): I Kappa B alpha Protein
I Kappa B-alpha Protein
IKappaB alpha
IKappaB-alpha
IKappaBalpha
Inhibitor alpha, NF-KappaB
Major Histocompatibility Complex Enhancer Binding Protein MAD3
Major Histocompatibility Complex Enhancer-Binding Protein MAD3
NF KappaB Inhibitor alpha
alpha, NF-KappaB Inhibitor
p40 Protein (IKappaB-alpha)
Tree number(s): D12.644.360.365.500
D12.776.260.420.500
D12.776.476.381.500
D12.776.930.326.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072000
Scope note: An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 139874-52-5
Public MeSH Note: 2017; NF-KAPPAB INHIBITOR ALPHA was indexed under DNA-BINDING PROTEINS 1999-2002 and under I-KAPPA B PROTEINS 2003-2016
History Note: 2017 (1991)
Related: Ankyrin Repeat MeSH
DeCS ID: 56547
Unique ID: D000072000
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/06/30
NF-KappaB Inhibitor alpha - Preferred
Concept UI M0190194
Scope note An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
Preferred term NF-KappaB Inhibitor alpha
Entry term(s) I Kappa B alpha Protein
I Kappa B-alpha Protein
IKappaB alpha
IKappaB-alpha
IKappaBalpha
Inhibitor alpha, NF-KappaB
Major Histocompatibility Complex Enhancer Binding Protein MAD3
Major Histocompatibility Complex Enhancer-Binding Protein MAD3
NF KappaB Inhibitor alpha
alpha, NF-KappaB Inhibitor
p40 Protein (IKappaB-alpha)



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey