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Descriptor English: I-kappa B Proteins
Descriptor Spanish: Proteínas I-kappa B
Descriptor Portuguese: Proteínas I-kappa B
Descriptor French: Protéines I-kappa B
Entry term(s): I kappa B
I kappa B Proteins
I-kappa B
IkB DNA Binding Proteins
IkB DNA-Binding Proteins
Tree number(s): D12.644.360.365
D12.776.260.420
D12.776.476.381
D12.776.930.326
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020672
Scope note: A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1998-1999)
Proto-Oncogene Proteins (1993-1998)
Public MeSH Note: 2000; see I KAPPA B 2000-2005, I KAPPA B PROTEINS was indexed under PROTO-ONCOGENE PROTEINS 1993-1998 & DNA-BINDING PROTEINS 1998-1999
History Note: 2006(2000)
Related: I-kappa B Kinase MeSH
NF-kappa B MeSH
Proto-Oncogene Proteins c-rel MeSH
DeCS ID: 34471
Unique ID: D020672
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2017/06/30
I-kappa B Proteins - Preferred
Concept UI M0328543
Scope note A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Preferred term I-kappa B Proteins
Entry term(s) I kappa B
I kappa B Proteins
I-kappa B
IkB DNA Binding Proteins
IkB DNA-Binding Proteins



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