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Descriptor English: Uncoupling Protein 2
Descriptor Spanish: Proteína Desacopladora 2
Descriptor proteína desacopladora 2
Entry term(s) miembro 8 de la familia 25 de transportadores de soluto
miembro 8 de la familia 25 de transportadores de solutos
proteína SLC25A8
proteína UCP2
proteína desacopladora mitocondrial 2
proteína desacopladora-2
proteína desacoplante 2
transportador de soluto, familia 25, miembro 8
transportador de solutos, familia 25, miembro 8
Scope note: Proteína desacopladora mitocondrial que se expresa en muchos tejidos y muestra la máxima expresión en el MÚSCULO ESQUELÉTICO. Regula la producción de ATP mitocondrial y la generación de ESPECIES REACTIVAS DE OXÍGENO.
Descriptor Portuguese: Proteína Desacopladora 2
Descriptor French: Protéine-2 de découplage
Entry term(s): Mitochondrial Uncoupling Protein 2
SLC25A8 Protein
Solute Carrier Family 25 Member 8
UCP2 Protein
Uncoupling Protein-2
Tree number(s): D12.776.157.530.937.598.750
D12.776.543.585.475.688.750
D12.776.543.585.937.696.750
D12.776.575.750.688.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071246
Scope note: A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; UNCOUPLING PROTEIN-2 was indexed under ION CHANNELS and MITOCHONDRIAL PROTEINS 2006-2016, under MEMBRANE TRANSPORT PROTEINS 2004-2006, and under PROTEINS 1997-2003
History Note: 2017 (1997)
DeCS ID: 56589
Unique ID: D000071246
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/26
Uncoupling Protein 2 - Preferred
Concept UI M0273842
Scope note A mitochondrial uncoupling protein that is expressed in many tissues and exhibits the greatest expression in SKELETAL MUSCLE. It regulates mitochondrial ATP production and the generation of REACTIVE OXYGEN SPECIES.
Preferred term Uncoupling Protein 2
Entry term(s) Mitochondrial Uncoupling Protein 2
SLC25A8 Protein
Solute Carrier Family 25 Member 8
UCP2 Protein
Uncoupling Protein-2



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