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Descriptor English: Signaling Lymphocytic Activation Molecule Family Member 1
Descriptor Spanish: Miembro 1 de la Familia de Moléculas Señalizadoras de la Activación Linfocitaria
Descriptor familia de moléculas señalizadoras de la activación linfocitaria, miembro 1
Entry term(s) antígeno CD150
proteína CDw150
proteína SLAM
proteína SLAMF1
receptor SLAM
receptor SLAMF1
Scope note: Receptor de la familia SLAM de 70 kDa que consta de un DOMINIO SIMILAR A INMUNOGLOBULINA y un DOMINIO DE INMUNOGLOBULINA C2. Se expresa principalmente en los TIMOCITOS y LINFOCITOS T activados, así como en los MACRÓFAGOS y CÉLULAS DENDRÍTICAS. Se une a los receptores SLAMF1 de otras células para mediar la maduración y proliferación de las células T. También es un receptor para el VIRUS DEL SARAMPIÓN.
Descriptor Portuguese: Membro 1 da Família de Moléculas de Sinalização da Ativação Linfocitária
Descriptor French: Membre-1 de la famille des molécules de signalisation de l'activation des lymphocytes
Entry term(s): Antigen, CD150
CD150 Antigen
CDw150 Protein
SLAM Protein
SLAM Receptor
SLAMF1 Protein
SLAMF1 Receptor
Tree number(s): D09.400.430.890.736.500
D12.776.395.550.736.500
D12.776.543.550.746.500
D12.776.543.750.705.970.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071177
Scope note: A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Registry Number: 169535-43-7
Public MeSH Note: 2017; SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE FAMILY MEMBER 1 was indexed under RECEPTORS, CELL SURFACE and ANTIGENS, CD 2007-2016; and under GLYCOPROTEINS and IMMUNOGLOBULINS 1995-2006
History Note: 2017 (1995)
DeCS ID: 56633
Unique ID: D000071177
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24
Signaling Lymphocytic Activation Molecule Family Member 1 - Preferred
Concept UI M0249384
Scope note A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
Preferred term Signaling Lymphocytic Activation Molecule Family Member 1
Entry term(s) Antigen, CD150
CD150 Antigen
CDw150 Protein
SLAM Protein
SLAM Receptor
SLAMF1 Protein
SLAMF1 Receptor



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