DeCS

Descriptor English:

CD48 Antigen

Descriptor Spanish:

Antígeno CD48

Spanish from Spain

Descriptor	antígeno CD48
Entry term(s)	antígeno Blast-1 antígeno MRC OX-45 antígeno de superficie BCM1 antígeno leucocitario MEM-102 antígeno p41 familia SLAM, miembro 2 familia de moléculas señalizadoras de activación linfocitaria, miembro 2 glicoproteína de transducción de señal 60 glucoproteína de transducción de señal 60 marcador BLAST-1 de activación de linfocitos B molécula señalizadora de activación linfocitaria 2 proteína SLAMF2
Scope note:	Proteína unida a GPI, de 40-45 KDa y perteneciente a la familia SLAM, que contiene dos DOMINIOS DE INMUNOGLOBULINA C2. Se expresa en la superficie de diversas células con función inmunitaria como los TIMOCITOS, los LINFOCITOS B y LINFOCITOS T maduros, las CÉLULAS ASESINAS NATURALES, las CÉLULAS DENDRÍTICAS, los MASTOCITOS y los EOSINÓFILOS. Se une a los receptores CD2 y 2B4 (CD244) para activar y modular la respuesta inmunitaria.

Descriptor Portuguese:

Antígeno CD48

Descriptor French:

Antigène CD48

Entry term(s):

Antigen, CD48
Antigen, MRC OX-45
Antigen, P41
B Lymphocyte Activation Marker BLAST 1
B-Lymphocyte Activation Marker BLAST-1
BCM1 Surface Antigen
Blast1 Antigen
Glycoprotein-60, Signal-Transducing
Leukocyte Antigen MEM 102
Leukocyte Antigen MEM-102
MEM-102, Leukocyte Antigen
MRC OX 45 Antigen
MRC OX-45 Antigen
P41 Antigen
SLAM Family Member 2
SLAMF2 Protein
Signal Transducing Glycoprotein 60
Signal-Transducing Glycoprotein-60
Signaling Lymphocytic Activation Molecule 2
Signaling Lymphocytic Activation Molecule Family Member 2
Surface Antigen, BCM1

Tree number(s):

D09.400.430.890.448.180
D09.400.430.890.736.250
D12.776.395.550.448.180
D12.776.395.550.736.250
D12.776.543.484.500.180
D12.776.543.550.418.180
D12.776.543.550.746.250
D12.776.543.750.705.970.250

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071178

Scope note:

A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.

Allowable Qualifiers:

AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure

Concept UI	M0180010
Scope note	A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.
Preferred term	CD48 Antigen
Entry term(s)	Antigen, CD48 Antigen, MRC OX-45 Antigen, P41 B Lymphocyte Activation Marker BLAST 1 B-Lymphocyte Activation Marker BLAST-1 BCM1 Surface Antigen Blast1 Antigen Glycoprotein-60, Signal-Transducing Leukocyte Antigen MEM 102 Leukocyte Antigen MEM-102 MEM-102, Leukocyte Antigen MRC OX 45 Antigen MRC OX-45 Antigen P41 Antigen SLAM Family Member 2 SLAMF2 Protein Signal Transducing Glycoprotein 60 Signal-Transducing Glycoprotein-60 Signaling Lymphocytic Activation Molecule 2 Signaling Lymphocytic Activation Molecule Family Member 2 Surface Antigen, BCM1

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