| Descriptor English: | Signaling Lymphocytic Activation Molecule Family | ||||||
| Descriptor Spanish: | 
                                Familia de Moléculas Señalizadoras de la Activación Linfocitaria                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Família de Moléculas de Sinalização da Ativação Linfocitária | ||||||
| Descriptor French: | Famille des molécules de signalisation de l'activation des lymphocytes | ||||||
| Entry term(s): | 
                                    SLAM Family Receptors SLAMF Receptors Signaling Lymphocytic Activation Molecule Family Receptors Signaling Lymphocytic Activation Molecule Receptors Signaling Lymphocytic Activation Molecules  | 
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| Tree number(s): | 
                                        D09.400.430.890.736 D12.776.395.550.736 D12.776.543.550.746 D12.776.543.750.705.970  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071176 | ||||||
| Scope note: | Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation. | 
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| Allowable Qualifiers: | 
                                                                        AD                                                            administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure  | 
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| Previous Indexing: | 
                                                Antigens, CD (1997-2016) Receptors, Cell Surface (1997-2016)  | 
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| Public MeSH Note: | 2017 | 
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| History Note: | 2017 | 
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| DeCS ID: | 56632 | ||||||
| Unique ID: | D000071176 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2017/05/24 | 
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                                        CHEMICALS AND DRUGS
 
Carbohydrates [D09]Carbohydrates - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins - 
                                    
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins 
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                        Signaling Lymphocytic Activation Molecule Family                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M000613385 | 
                                
| Scope note | Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation. | 
| Preferred term | Signaling Lymphocytic Activation Molecule Family | 
| Entry term(s) | 
                                        
                                                                                            SLAM Family Receptors                                                 SLAMF Receptors Signaling Lymphocytic Activation Molecule Family Receptors Signaling Lymphocytic Activation Molecule Receptors Signaling Lymphocytic Activation Molecules  | 
                                
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