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Descriptor English: Angiopoietin-like Proteins
Descriptor Spanish: Proteínas Similares a la Angiopoyetina
Descriptor proteínas similares a la angiopoyetina
Entry term(s) proteína relacionada con la angiopoyetina
proteína similar a la angiopoyetina
Scope note: Familia de proteínas estructuralmente similares a las ANGIOPOYETINAS pero que no se unen a los receptores de angiopoyetina. Se caracterizan por contar con un dominio en hélice superenrollada aminoterminal, una región de unión y un dominio carboxiterminal similar al FIBRINÓGENO, con la excepción de la ANGPTL8 que carece de este último dominio. Intervienen en distintos procesos fisiológicos y del desarrollo, como la INFLAMACIÓN, el metabolismo lipídico, la actividad de las células madre hematopoyéticas y las metástasis cancerosas.
Descriptor Portuguese: Proteínas Semelhantes a Angiopoietina
Descriptor French: Protéines semblables à l'angiopoïétine
Entry term(s): Angiopoietin like Protein
Angiopoietin like Proteins
Angiopoietin related Protein
Angiopoietin-like Protein
Angiopoietin-related Protein
Tree number(s): D12.644.276.100.050
D12.776.467.100.050
D23.529.100.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075802
Scope note: A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Angiopoietins (2004-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57047
Unique ID: D000075802
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Angiopoietin-like Proteins - Preferred
Concept UI M000631467
Scope note A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.
Preferred term Angiopoietin-like Proteins
Entry term(s) Angiopoietin like Protein
Angiopoietin like Proteins
Angiopoietin related Protein
Angiopoietin-like Protein
Angiopoietin-related Protein



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