| Descriptor English: | Angiopoietin-Like Protein 4 | ||||||
| Descriptor Spanish: |
Proteína 4 Similar a la Angiopoyetina
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| Descriptor Portuguese: | Proteína 4 Semelhante a Angiopoietina | ||||||
| Descriptor French: | Protéine-4 similaire à l'angiopoïétine | ||||||
| Entry term(s): |
ANGPTL4 Protein Angiopoietin like 4 Protein Angiopoietin like Protein 4 Angiopoietin related Protein 4 Angiopoietin-like 4 Protein Angiopoietin-related Protein 4 |
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| Tree number(s): |
D12.644.276.100.050.400 D12.776.467.100.050.400 D23.529.100.050.400 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075803 | ||||||
| Scope note: | A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Angiopoietins (2004-2017) Blood Proteins (2000-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57048 | ||||||
| Unique ID: | D000075803 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Angiopoietin-Like Protein 4
- Preferred
| Concept UI |
M000631469 |
| Scope note | A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis. |
| Preferred term | Angiopoietin-Like Protein 4 |
| Entry term(s) |
ANGPTL4 Protein Angiopoietin like 4 Protein Angiopoietin like Protein 4 Angiopoietin related Protein 4 Angiopoietin-like 4 Protein Angiopoietin-related Protein 4 |
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